"The US Food and Drug Administration (FDA) has approved a quarterly injection form of paliperidone (Invega Trinza, Janssen Pharmaceuticals) for schizophrenia, the company announced today.
Janssen Pharmaceuticals already markets a "...
brand of chlorpromazine antipsychotic• tranquilizer • antiemetic
Thorazine (chlorpromazine) is 10-(3-dimethylaminopropyl)-2-chlorphenothiazine, a dimethylamine derivative of phenothiazine. It is present in oral and injectable forms as the hydrochloride salt, and in the suppositories as the base.
Tablets — Each round, orange, coated tablet contains chlorpromazine hydrochloride as follows: 10 mg imprinted SKF and T73; 25 mg imprinted SKF and T74; 50 mg imprinted SKF and T76; 100 mg imprinted SKF and T77; 200 mg imprinted SKF and T79. Inactive ingredients consist of benzoic acid, croscarmellose sodium, D&C Yellow No. 10, FD&C Blue No. 2, FD&C Yellow No. 6, gelatin, hydroxypropyl methylcellulose, lactose, magnesium stearate, methylparaben, polyethylene glycol, propylparaben, talc, titanium dioxide and trace amounts of other inactive ingredients.
Spansule® sustained release capsules — Each Thorazine (chlorpromazine) Spansule® capsule is so prepared that an initial dose is released promptly and the remaining medication is released gradually over a prolonged period.
Each capsule, with opaque orange cap and natural body, contains chlorpromazine hydrochloride as follows: 30 mg imprinted SKF and T63; 75 mg imprinted SKF and T64; 150 mg imprinted SKF and T66. Inactive ingredients consist of benzyl alcohol, calcium sulfate, cetylpyridinium chloride, FD&C Yellow No. 6, gelatin, glyceryl distearate, glyceryl monostearate, iron oxide, povidone, silicon dioxide, sodium lauryl sulfate, starch, sucrose, titanium dioxide, wax and trace amounts of other inactive ingredients.
Ampuls — Each mL contains, in aqueous solution, chlorpromazine hydrochloride, 25 mg; ascorbic acid, 2 mg; sodium bisulfite, 1 mg; sodium chloride, 6 mg; sodium sulfite, 1 mg.
Multi-Dose Vials — Each mL contains, in aqueous solution, chlorpromazine hydrochloride, 25 mg; ascorbic acid, 2 mg; sodium bisulfite, 1 mg; sodium chloride, 1 mg; sodium sulfite, 1 mg; benzyl alcohol, 2%, as a preservative.
Syrup — Each 5 mL (1 teaspoonful) of clear, orange-custard flavored liquid contains chlorpromazine hydrochloride, 10 mg. Inactive ingredients consist of citric acid, flavors, sodium benzoate, sodium citrate, sucrose and water.
Suppositories — Each suppository contains chlorpromazine, 25 or 100 mg, glycerin, glyceryl monopalmitate, glyceryl monostearate, hydrogenated coconut oil fatty acids and hydrogenated palm kernel oil fatty acids.
What are the possible side effects of chlorpromazine (Thorazine)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking chlorpromazine and call your doctor at once if you have a serious side effect such as:
- twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;
- tremor (uncontrolled shaking), drooling, trouble swallowing, problems with balance or walking;
- feeling restless, jittery, or agitated;
- feeling like you might pass out;
- seizure (black-out or...
Last reviewed on RxList: 1/18/2017
This monograph has been modified to include the generic and brand name in many instances.
Additional Thorazine Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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