July 2, 2015
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Thorazine

"The US Food and Drug Administration (FDA) has approved a quarterly injection form of paliperidone (Invega Trinza, Janssen Pharmaceuticals) for schizophrenia, the company announced today.

Janssen Pharmaceuticals already markets a "...

Thorazine




CLINICAL PHARMACOLOGY

ACTIONS

The precise mechanism whereby the therapeutic effects of chlorpromazine are produced is not known. The principal pharmacological actions are psychotropic. It also exerts sedative and antiemetic activity.

Chlorpromazine has actions at all levels of the central nervous system— primarily at subcortical levels— as well as on multiple organ systems. Chlorpromazine has strong antiadrenergic and weaker peripheral anticholinergic activity; ganglionic blocking action is relatively slight. It also possesses slight antihistaminic and antiserotonin activity.

Last reviewed on RxList: 6/2/2008
This monograph has been modified to include the generic and brand name in many instances.

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