"Feb. 22, 2011 -- The FDA has issued a safety announcement notifying health care professionals that it has updated the pregnancy section of drug labels for the entire class of antipsychotic medications.
Antipsychotic drugs are used to "...
- Clinician Information:
Thorazine Patient Information including How Should I Take
In this Article
- What is chlorpromazine (Thorazine)?
- What are the possible side effects of chlorpromazine (Thorazine)?
- What is the most important information I should know about chlorpromazine (Thorazine)?
- What should I discuss with my healthcare provider before taking chlorpromazine (Thorazine)?
- How should I take chlorpromazine (Thorazine)?
- What happens if I miss a dose (Thorazine)?
- What happens if I overdose (Thorazine)?
- What should I avoid while taking chlorpromazine (Thorazine)?
- What other drugs will affect chlorpromazine (Thorazine)?
- Where can I get more information?
What should I discuss with my healthcare provider before taking chlorpromazine (Thorazine)?
Chlorpromazine is not for use in psychotic conditions related to dementia. Chlorpromazine may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.
Do not use chlorpromazine if you have brain damage, bone marrow depression, or are also using large amounts of alcohol or medicines that make you sleepy. Do not use if you are allergic to chlorpromazine or other phenothiazines such as fluphenazine (Permitil), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), promethazine (Adgan, Pentazine, Phenergan), thioridazine (Mellaril), or trifluoperazine (Stelazine).
To make sure you can safely take chlorpromazine, tell your doctor if you have any of these other conditions:
- liver or kidney disease;
- heart disease or high blood pressure;
- severe asthma, emphysema, or other breathing problem;
- past or present breast cancer;
- low levels of calcium in your blood (hypocalcemia);
- adrenal gland tumor (pheochromocytoma);
- an enlarged prostate or urination problems;
- a history of seizures;
- Parkinson's disease; or
- if you have ever had a serious side effect while using chlorpromazine or any other phenothiazine.
Tell your doctor if you will be exposed to extreme heat or cold, or to insecticide poisons while you are taking chlorpromazine.
Taking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. If you become pregnant while taking chlorpromazine, do not stop taking it without your doctor's advice.
Chlorpromazine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Talk with your doctor before giving this medication to a child who has been ill with a fever or flu symptoms.
Older adults may be more likely to have side effects from this medication.
How should I take chlorpromazine (Thorazine)?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.
This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using chlorpromazine.
If you need to have any type of x-ray scan or MRI of your spinal cord, tell the doctor ahead of time that you are using chlorpromazine. You may need to stop using the medicine for a short time.
Do not stop using chlorpromazine suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using chlorpromazine.
Store at room temperature away from moisture and heat.
Additional Thorazine Information
- Thorazine Drug Interactions Center: chlorpromazine oral
- Thorazine Side Effects Center
- Thorazine FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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