May 24, 2016

Threonine

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How does Threonine work?

Threonine is changed in the body to a chemical called glycine. Glycine works in the brain to reduce constant and unwanted muscle contractions (spasticity).

Are there safety concerns?

Threonine is POSSIBLY SAFE when doses of up to 4 grams daily are taken by mouth for up to 12 months. Some people experience minor side effects such as stomach upset, headache, nausea, and skin rash.

Special Precautions & Warnings:

Pregnancy and breast-feeding: There is not enough reliable information about the safety of taking threonine if you are pregnant or breast-feeding. Stay on the safe side and avoid use.

Amyotrophic lateral sclerosis (Lou Gehrig's disease):There is some concern that threonine might decrease lung function in patients with ALS. In one study, ALS patients taking 1 gram of threonine four times per day for 6 months had significantly reduced lung function compared to patients who did not receive threonine. More evidence is needed to determine if threonine was actually at fault.


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Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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