"The cystic fibrosis (CF) drug Orkambi (Vertex Pharmaceuticals) has received a green light from the European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP).
Orkambi is a fixed-dose oral combination "...
(Generic versions may still be available.)
FOR INTRAVENOUS ADMINISTRATION
Chemically, Thyrel® TRH (protirelin) is identified as 5-oxo-L-prolyl-L-histidyl-L-proline amide. It is a synthetic tripeptide that is believed to be structurally identical to the naturally-occurring thyrotropin-releasing hormone produced by the hypothalamus. The CAS Registry Number is 24305-27-9. The structual formula is:
Thyrel TRH (protirelin) is supplied as 1 mL ampuls. Each ampul contains 500 µg protirelin in a sterile nonpyrogenic isotonic saline solution having a pH of approximately 6.5. In addition, each ampul contains sodium chloride 9.0 mg, Water for Injection, hydrochloric acid and sodium hydroxide as needed to adjust pH. Thyrel TRH (protirelin) is intended for intravenous administration.
Last reviewed on RxList: 1/18/2005
This monograph has been modified to include the generic and brand name in many instances.
Additional Thyrel Trh Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Find out what women really need.