home > drugs a-z list > thyrogen (thyrotropin alfa for injection) drug center > thyrogen (thyrotropin alfa for injection) drug - overdosage and contraindications

There has been no reported experience of overdose in humans. However, in clinical trials, three patients experienced symptoms after receiving Thyrogen (thyrotropin alfa for injection) doses higher than those recommended. Two patients had nausea after a 2.7 mg IM dose, and in one of these patients, the event was accompanied by weakness, dizziness and headache. Another patient experienced nausea, vomiting and hot flashes after a 3.6 mg IM dose.

In addition, one patient experienced symptoms after receiving Thyrogen (thyrotropin alfa for injection) intravenously. This patient received 0.3 mg Thyrogen (thyrotropin alfa for injection) as a single intravenous bolus and, 15 minutes later experienced severe nausea, vomiting, diaphoresis, hypotension (BP decreased from 115/66 mm Hg to 81/44 mm Hg) and tachycardia (pulse increased from 75 to 117 bpm).

No information provided.

Last reviewed on RxList: 9/22/2008
This monograph has been modified to include the generic and brand name in many instances.