"Vemurafenib (Zelboraf, Roche/Genentech), a BRAF inhibitor marketed for use in the treatment of melanoma, has now shown activity in patients with refractory papillary thyroid cancer.
For the approximately 25% to 50% of patients "...
Thyrolar Consumer (continued)
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious effects of high thyroid hormone levels occur: diarrhea, bone pain, headache, mental/mood changes (e.g., nervousness, mood swings), shaking (tremor), sensitivity to heat, increased sweating, tiredness.
Seek immediate medical attention if any of these rare but very serious effects of high thyroid hormone levels occur: chest pain, fast/pounding/irregular heartbeat, seizures, swelling of the ankles/feet.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the Thyrolar (liotrix) Side Effects Center for a complete guide to possible side effects
PRECAUTIONS: Before taking liotrix, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: increased thyroid hormones (thyrotoxicosis), a heart attack (acute myocardial infarction), adrenal gland problem (e.g., uncorrected adrenal insufficiency).
Before using this medication, tell your doctor or pharmacist your medical history, especially of: heart disease (e.g., coronary artery disease, irregular heartbeat), high blood pressure, diabetes, other hormone disorders (e.g., decreased pituitary hormone).
If you have diabetes, this medication may increase your blood sugar levels. Check your blood glucose levels regularly as directed by your doctor. Tell your doctor immediately if you have symptoms of high blood sugar, such as increased thirst and urination. Your anti-diabetic medication or diet may need to be adjusted.
Before having surgery, tell your doctor or dentist that you are taking this medication.
Caution is advised when using this drug in the elderly because they may be more sensitive to the effects on the heart caused by high thyroid hormone level.
Current information shows that this drug may be used during pregnancy. Tell your doctor if you are pregnant or if you become pregnant because your dose may need to be adjusted.
Small amounts of this medication pass into breast milk. Consult your doctor before breast-feeding.
Additional Thyrolar Information
Thyrolar - User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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