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Ticlid

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Ticlid

OVERDOSE

One case of deliberate overdosage with TICLID (ticlopidine hcl) has been reported by a foreign postmarketing surveillance program. A 38-year-old male took a single 6000-mg dose of TICLID (ticlopidine hcl) (equivalent to 24 standard 250-mg tablets). The only abnormalities reported were increased bleeding time and increased SGPT. No special therapy was instituted and the patient recovered without sequelae.

Single oral doses of ticlopidine at 1600 mg/kg and 500 mg/kg were lethal to rats and mice, respectively. Symptoms of acute toxicity were GI hemorrhage, convulsions, hypothermia, dyspnea, loss of equilibrium and abnormal gait.

CONTRAINDICATIONS

The use of TICLID (ticlopidine hcl) is contraindicated in the following conditions:

Last reviewed on RxList: 6/10/2008
This monograph has been modified to include the generic and brand name in many instances.

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