"The US Food and Drug Administration (FDA) has approved an expanded indication for onabotulinum toxin A (Botox, Actavis) for the treatment of adults with upper limb spasticity, according to a company news release.
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(trimethobenzamide hydrochloride) Capsules
Chemically, trimethobenzamide HCl is N-[p-[2-(dimethylamino)ethoxy]benzyl]-3,4,5trimethoxybenzamide monohydrochloride. It has a molecular weight of 424.93 and the following structural formula:
Capsules: Each 300-mg Tigan (trimethobenzamide hydrochloride capsules) capsule for oral use contains trimethobenzamide hydrochloride equivalent to 300 mg. The capsule has an opaque purple cap marked “Tigan (trimethobenzamide hydrochloride capsules) ” and an opaque purple body marked “M079”. Inactive Ingredients: D&C Red No. 28, FD&C Blue No. 1, lactose, magnesium stearate, starch and titanium dioxide.
What are the possible side effects of trimethobenzamide (Tigan)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have any of these serious side effects:
- jaundice (yellowing of the skin or eyes);
- seizure (convulsions);
- easy bruising or bleeding, unusual weakness;
- tremor (uncontrolled shaking); or
- muscle cramps, severe muscle spasms.
Continue using trimethobenzamide and talk with your doctor if you have any of...
What are the precautions when taking trimethobenzamide hydrochloride capsules (Tigan)?
Before taking trimethobenzamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: high fever, kidney problems, stomach/intestinal problems (e.g., appendicitis), swelling/disease of the brain (encephalitis/encephalopathy), a serious loss of body water (dehydration), mineral (electrolyte) imbalance.
This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such...
Last reviewed on RxList: 1/23/2009
This monograph has been modified to include the generic and brand name in many instances.
Additional Tigan Information
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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