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Tigan

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Tigan

Tigan

INDICATIONS

Tigan (trimethobenzamide hydrochloride capsules) is indicated for the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.

DOSAGE AND ADMINISTRATION

(See WARNINGS and PRECAUTIONS)

Dosage should be adjusted according to the indication for therapy, severity of symptoms and the response of the patient.

Geriatric Patients

Dose adjustment such as reducing the total dose administered at each dosing or increasing the dosing interval should be considered in elderly patients with renal impairment (creatinine clearance ≤ 70 mL/min/1.73m²). Final dose adjustment should be based upon integration of clinical efficacy and safety considerations. (See CLINICAL PHARMACOLOGY and PRECAUTIONS).

Patients with Renal Impairment

In subjects with renal impairment (creatinine clearance ≤ 70 mL/min/1.73m²), dose adjustment such as reducing the total dose administered at each dosing or increasing the dosing interval should be considered. (See CLINICAL PHARMACOLOGY and PRECAUTIONS).

Capsules, 300 mg

Usual Adult Dosage

One 300 mg capsule t.i.d. or q.i.d.

Storage

Store at 25°C (77°F). Excursions permitted to 15–30°C (59–86°F).

[See USP Controlled Room Temperature]

HOW SUPPLIED

Capsules, 300 mg trimethobenzamide hydrochloride each, bottles of 100 NDC 61570-079-01 300 mg 100's

Prescribing Information as of April 2008. Distributed By: Monarch Pharmaceuticals, Inc., Bristol, TN 37620 (A wholly owned subsidiary of King Pharmaceuticals, Inc.) Manufactured By: King Pharmaceuticals, Inc., Bristol, TN 37620. FDA revision date: 12/2/2008

Last reviewed on RxList: 1/23/2009
This monograph has been modified to include the generic and brand name in many instances.

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