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Tikosyn

What is atrial fibrillation?

Atrial fibrillation (AF) is the most common, abnormal rhythm of the heart.

The heart contracts (beats) and pumps blood with a regular rhythm, for example, at a rate of 60 beats per minute there is a beat every second. The heart may beat faster or slower with a shorter or longer interval between beats, but at any one rate the interval between beats is constant. This regular rhythm occurs as a result of regular electrical discharges (currents) that travel through the heart and cause the muscle of the heart to contract. In atrial fibrillation, the electrical discharges are irregular and rapid and, as a result, the heart beats irregularly and, usually, rapidly.

Atrial fibrillation is common; half a million new cases are diagnosed yearly in the U.S., and billions of dollars are spent annually on its diagnosis and treatment.

What causes atrial fibrillation?

Normal function of the he...

Tikosyn

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Tikosyn Drug Center

Medical Editor: John P. Cunha, DO, FACOEP

Tikosyn (dofetilide) is used to help keep the heart beating normally in people with certain heart rhythm disorders of the atrium (the upper chambers of the heart). Tikosyn is used in people with atrial fibrillation or atrial flutter. It is an antiarrhythmic drug. Common side effects include headache, dizziness, or nausea.

The usual recommended dose of Tikosyn is 500 mcg twice daily. When starting, restarting, or increasing the dose, you will need to stay in the hospital for at least 3 days for monitoring. Tikosyn may interact with diuretics (water pills), HIV/AIDS medicine, drugs that can affect heart rhythm, narcotics, antibiotics, antidepressants, medicines to treat psychiatric disorders, or heart rhythm medicine. Tell your doctor all medications you are taking. During pregnancy, Tikosyn should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Our Tikosyn (dofetilide) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Tikosyn Prescribing Information: Indications & Dosage

TIKOSYN® (dofetilide) Structural Formula Illustration

Maintenance of Normal Sinus Rhythm (Delay in AF/AFl Recurrence)

TIKOSYN is indicated for the maintenance of normal sinus rhythm (delay in time to recurrence of atrial fibrillation/atrial flutter [AF/AFl]) in patients with atrial fibrillation/atrial flutter of greater than one week duration who have been converted to normal sinus rhythm. Because TIKOSYN can cause life threatening ventricular arrhythmias, it should be reserved for patients in whom atrial fibrillation/atrial flutter is highly symptomatic.

In general, antiarrhythmic therapy for atrial fibrillati...

Read the complete drug monograph for Tikosyn »

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Tikosyn Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • fast or pounding heartbeat, chest pain, shortness of breath; or
  • feeling like you might pass out.

Less serious side effects may include:

  • headache or back pain;
  • dizziness;
  • nausea, diarrhea, stomach pain;
  • sleep problems (insomnia);
  • stuffy or runny nose,...

Read the complete patient information for Tikosyn »

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Tikosyn Consumer Information: Uses

This medication is used to treat certain types of serious (possibly fatal) irregular heartbeat (such as atrial fibrillation/flutter). It is used to restore normal heart rhythm and maintain a regular, steady heartbeat. Dofetilide is known as an anti-arrhythmic drug. It works by blocking the activity of certain electrical signals in the heart that can cause an irregular heartbeat. Treating an irregular heartbeat can decrease the risk for blood clots, and this effect can reduce your risk of heart attack or stroke.

HOW TO USE: Read the Medication Guide ...

Read the complete consumer information for Tikosyn »

What is Tikosyn Consumer Information?

Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More

Tikosyn - User Reviews

Tikosyn User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Tikosyn sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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