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Atrial fibrillation (AF) is the most common, abnormal rhythm of the heart.
The heart contracts (beats) and pumps blood with a regular rhythm, for example,
at a rate of 60 beats per minute there is a beat every second. The heart may
beat faster or slower with a shorter or longer interval between beats, but at
any one rate the interval between beats is constant. This regular rhythm occurs
as a result of regular electrical discharges (currents) that travel through the
heart and cause the muscle of the heart to contract. In atrial fibrillation, the electrical
discharges are irregular and rapid and, as a result, the heart beats irregularly
and, usually, rapidly.
Atrial fibrillation is common; half a million new cases are diagnosed yearly
in the U.S., and billions of dollars are spent annually on its diagnosis and
treatment.
Normal function of the he...
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Medical Editor: John P. Cunha, DO, FACOEP
Tikosyn (dofetilide) is used to help keep the heart beating normally in people with certain heart rhythm disorders of the atrium (the upper chambers of the heart). Tikosyn is used in people with atrial fibrillation or atrial flutter. It is an antiarrhythmic drug. Common side effects include headache, dizziness, or nausea.
The usual recommended dose of Tikosyn is 500 mcg twice daily. When starting, restarting, or increasing the dose, you will need to stay in the hospital for at least 3 days for monitoring. Tikosyn may interact with diuretics (water pills), HIV/AIDS medicine, drugs that can affect heart rhythm, narcotics, antibiotics, antidepressants, medicines to treat psychiatric disorders, or heart rhythm medicine. Tell your doctor all medications you are taking. During pregnancy, Tikosyn should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.
Our Tikosyn (dofetilide) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
TIKOSYN is indicated for the maintenance of normal sinus rhythm (delay in time to recurrence of atrial fibrillation/atrial flutter [AF/AFl]) in patients with atrial fibrillation/atrial flutter of greater than one week duration who have been converted to normal sinus rhythm. Because TIKOSYN can cause life threatening ventricular arrhythmias, it should be reserved for patients in whom atrial fibrillation/atrial flutter is highly symptomatic.
In general, antiarrhythmic therapy for atrial fibrillati...
Read the complete drug monograph for Tikosyn »
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
Read the complete patient information for Tikosyn »
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
HOW TO USE: Read the Medication Guide ...
Read the complete consumer information for Tikosyn »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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