Tilade (Nedocromil Inhalation Aerosol) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 10, 2012

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Asthma »

Myths, facts, and statistics about asthma

Before we present the typical symptoms of asthma, we should dispel some common myths about this condition. This is best achieved by conducting a short true or false quiz.

T or F - Asthma is "all in the mind."
T or F - You will "grow out of it."
T or F - Asthma can be cured, so it is not serious and nobody dies from it.
T or F - You are likely to develop asthma if someone in your family has it.
T or F - You can "catch" asthma from someone else who has it.
T or F - Moving to a different location, such as the desert, can cure asthma.
T or F - People with asthma should not exercise.
T or F - Asthma is best controlled when one has an asthma management plan designed by your doctor. This should include the medications used for quick relief as well as maintenance therapy.
T or F - Medications used to treat asthma are habit...

Read the Asthma article »

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Tilade® Inhaler
(nedocromil sodium) Inhalation Aerosol

DRUG DESCRIPTION

Tilade (nedocromil sodium) is an inhaled anti-inflammatory agent for the preventive management of asthma. Nedocromil sodium is a pyranoquinoline with the chemical name 4H-Pyrano[3,2-g]quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-, disodium salt, and it has a molecular weight of 415.3. The empirical formula is C₁₉H₁₅NNa₂O₇. Nedocromil sodium, a yellow powder, is soluble in water.

The molecular structure of nedocromil sodium is:

Tilade (nedocromil sodium) Structural Formula Illustration

Chemical Class: Pyranoquinoline

Tilade Inhaler (nedocromil sodium inhalation aerosol) is a pressurized metered-dose aerosol suspension for oral inhalation containing micronized nedocromil sodium and sorbitan trioleate, as well as dichlorotetrafluoroethane and dichlorodifluoromethane as propellants. Each Tilade canister contains 210 mg nedocromil sodium. Each actuation meters 2.00 mg nedocromil sodium from the valve and delivers 1.75 mg nedocromil sodium from the mouthpiece. Each 16.2 g canister provides at least 104 metered actuations. After 104 metered actuations, the amount delivered per actuation may not be consistent and the unit should be discarded.

Each Tilade (nedocromil inhalation aerosol) Inhaler canister must be primed with 3 actuations prior to the first use. If a canister remains unused for more than 7 days, then it should be reprimed with 3 actuations.

What are the possible side effects of nedocromil inhalation (Tilade)?

Serious side effects from nedocromil inhalation are not likely to occur. Seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to use nedocromil inhalation and talk to your doctor if you experience