"Following the 2014 Ebola outbreak in West Africa that took the lives of more than 11,200 people in the region, the National Eye Institute, part of the National Institutes of Health, has deployed a team of clinicians and technical experts to Monro"...
DOSAGE AND ADMINISTRATION
TIMOPTIC Ophthalmic Solution is available in concentrations of 0.25 and 0.5%. The usual starting dose is one drop of 0.25% TIMOPTIC in the affected eye(s) twice a day. If the clinical response is not adequate, the dosage may be changed to one drop of 0.5% solution in the affected eye(s) twice a day.
Since in some patients the pressure-lowering response to TIMOPTIC may require a few weeks tostabilize, evaluation should include a determination of intraocular pressure after approximately 4 weeks oftreatment with TIMOPTIC.
If the intraocular pressure is maintained at satisfactory levels, the dosage schedule may be changed to one drop once a day in the affected eye(s). Because of diurnal variations in intraocular pressure, satisfactory response to the once-a-day dose is best determined by measuring the intraocular pressure at different times during the day.
Dosages above one drop of 0.5% TIMOPTIC twice a day generally have not been shown to produce further reduction in intraocular pressure. If the patient's intraocular pressure is still not at a satisfactory level on this regimen, concomitant therapy with other agent(s) for lowering intraocular pressure can be instituted. The concomitant use of two topical beta-adrenergic blocking agents is not recommended [see DRUG INTERACTIONS, Beta-adrenergic blocking agents].
TIMOPTIC® (timolol maleate ophthalmic solution) is a clear, colorless to light yellow solution.
TIMOPTIC 0.25% timolol equivalent is supplied in a white low density polyethylene (LDPE) bottle with a controlled drop tip and a yellow polypropylene cap as follows:
NDC 24208-812-05: 5 mL in a 7.5 mL capacity bottle
TIMOPTIC 0.5% timolol equivalent is supplied in a white low density polyethylene (LDPE) bottle with a controlled drop tip and a yellow polypropylene cap as follows:
NDC 24208-813-05: 5 mL in a 7.5 mL capacity
NDC 24208-813-10: 10 mL in a 10 mL capacity bottle
Store at 15 to 25°C (59 to 77°F). Protect from freezing. Protect from light.
Distributed by: Bausch + Lomb, a division of Valeant Pharmaceuticals North America LLC, Bridgewater, NJ 08807 USA. Revised: Apr 2016This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 9/1/2016
Additional Timoptic Information
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