April 25, 2017
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Timoptic

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Timoptic




Indications
Dosage
How Supplied

INDICATIONS

TIMOPTIC Ophthalmic Solution is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.

DOSAGE AND ADMINISTRATION

TIMOPTIC Ophthalmic Solution is available in concentrations of 0.25 and 0.5%. The usual starting dose is one drop of 0.25% TIMOPTIC in the affected eye(s) twice a day. If the clinical response is not adequate, the dosage may be changed to one drop of 0.5% solution in the affected eye(s) twice a day.

Since in some patients the pressure-lowering response to TIMOPTIC may require a few weeks tostabilize, evaluation should include a determination of intraocular pressure after approximately 4 weeks oftreatment with TIMOPTIC.

If the intraocular pressure is maintained at satisfactory levels, the dosage schedule may be changed to one drop once a day in the affected eye(s). Because of diurnal variations in intraocular pressure, satisfactory response to the once-a-day dose is best determined by measuring the intraocular pressure at different times during the day.

Dosages above one drop of 0.5% TIMOPTIC twice a day generally have not been shown to produce further reduction in intraocular pressure. If the patient's intraocular pressure is still not at a satisfactory level on this regimen, concomitant therapy with other agent(s) for lowering intraocular pressure can be instituted. The concomitant use of two topical beta-adrenergic blocking agents is not recommended [see DRUG INTERACTIONS, Beta-adrenergic blocking agents].

HOW SUPPLIED

TIMOPTIC® (timolol maleate ophthalmic solution) is a clear, colorless to light yellow solution.

TIMOPTIC 0.25% timolol equivalent is supplied in a white low density polyethylene (LDPE) bottle with a controlled drop tip and a yellow polypropylene cap as follows:

NDC 24208-812-05: 5 mL in a 7.5 mL capacity bottle

TIMOPTIC 0.5% timolol equivalent is supplied in a white low density polyethylene (LDPE) bottle with a controlled drop tip and a yellow polypropylene cap as follows:

NDC 24208-813-05: 5 mL in a 7.5 mL capacity bottle
NDC 24208-813-10: 10 mL in a 10 mL capacity bottle

Storage

Store at 15 to 25°C (59 to 77°F). Protect from freezing. Protect from light.

Distributed by: Bausch + Lomb, a division of Valeant Pharmaceuticals North America LLC, Bridgewater, NJ 08807 USA. Revised: Apr 2016

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 9/1/2016

Indications
Dosage
How Supplied

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