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WARNING: POTENTIAL RISK FOR CARCINOGENICITY
Carcinogenicity has been seen in mice and rats treated chronically with metronidazole, another nitroimidazole agent (13.1). Although such data have not been reported for tinidazole, the two drugs are structurally related and have similar biologic effects. Its use should be reserved for the conditions described in INDICATIONS AND USAGE.
Tinidazole is a synthetic antiprotozoal and antibacterial agent. It is 1-[2-(ethylsulfonyl)ethyl]-2-methyl-5-nitroimidazole, a second-generation 2-methyl-5-nitroimidazole, which has the following chemical structure:
Tindamax pink oral tablets contain 250 mg or 500 mg of tinidazole. Inactive ingredients include croscarmellose sodium, FD&C Red 40 lake, FD&C Yellow 6 lake, hypromellose, magnesium stearate, microcrystalline cellulose, polydextrose, polyethylene glycol, pregelatinized corn starch, titanium dioxide, and triacetin.
What are the possible side effects of tinidazole (Tindamax)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- fever, chills, body aches, flu symptoms;
- numbness, burning pain, or tingly feeling; or
- seizure (convulsions).
Less serious side effects may include:
- vaginal itching or discharge;
- nausea, vomiting, loss of appetite, indigestion;
- constipation, diarrhea, stomach cramps;
- feeling weak or...
What are the precautions when taking tinidazole (Tindamax)?
Before taking tinidazole, tell your doctor or pharmacist if you are allergic to it; or to metronidazole; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood problems (e.g., low white blood cells), brain or nervous system disorders (e.g., neuropathy, seizures), untreated fungal/yeast infection, kidney dialysis, liver disease.
While taking this medication and for at least 3 days after your last dose, do not drink alcoholic beverages or take products that contain alcohol/propylene glycol. Doing so may cause severe stomach upset, nausea, vomiting,...
Last reviewed on RxList: 8/14/2007
This monograph has been modified to include the generic and brand name in many instances.
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