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There are no reported overdoses with tinidazole in humans.

Treatment of Overdosage: There is no specific antidote for the treatment of overdosage with tinidazole; therefore, treatment should be symptomatic and supportive. Gastric lavage may be helpful. Hemodialysis can be considered because approximately 43% of the amount present in the body is eliminated during a 6-hour hemodialysis session.

The use of tinidazole is contraindicated:

• In patients with a previous history of hypersensitivity to tinidazole or other nitroimidazole derivatives. Reported reactions have ranged in severity from urticaria to Stevens-Johnson syndrome [see ADVERSE REACTIONS].
• During first trimester of pregnancy [see Use in Specific Populations].
• In nursing mothers: Interruption of breast-feeding is recommended during tinidazole therapy and for 3 days following the last dose [see Use in Specific Populations].

Last reviewed on RxList: 8/14/2007
This monograph has been modified to include the generic and brand name in many instances.