- Patient Information:
Details with Side Effects
NOT FOR TREATMENT OF OBESITY OR FOR WEIGHT LOSS
- Thyroid hormones, including TIROSINT, either alone or with other therapeutic agents, should not be used for the treatment of obesity or for weight loss.
- In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction.
- Larger doses may produce serious or even life threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [See ADVERSE REACTIONS, DRUG INTERACTIONS, and OVERDOSAGE].
TIROSINT (levothyroxine sodium) is L-thyroxine. The orally
administered gelatin capsules contain synthetic L-3,3',5,5'-tetraiodothyronine
sodium salt [levothyroxine (T4) sodium]. Synthetic T4 is
chemically identical to that produced in the human thyroid gland. Levothyroxine
(T4) sodium has an empirical formula of C15H10I4NNaO4
• x H2O (where x = 5), molecular weight of 798.86 g/mol (anhydrous),
and structural formula as shown:
The inactive ingredients in TIROSINT are gelatin, glycerin and water.
Last reviewed on RxList: 3/14/2012
This monograph has been modified to include the generic and brand name in many instances.
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