"DENVER â€” New data shed more light on the specific risks of congenital birth defects associated with the Graves' disease drug methimazole (MMI) and the timing of the teratogenic effects.
The results indicate that there were significant"...
(levothyroxine sodium) Oral Solution
NOT FOR TREATMENT OF OBESITY or FOR WEIGHT LOSS
Thyroid hormones, including TIROSINT-SOL, either alone or with other therapeutic agents, should not be used for the treatment of obesity or for weight loss.
In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction.
Larger doses may produce serious or even life threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see ADVERSE REACTIONS, DRUG INTERACTIONS, and OVERDOSAGE].
TIROSINT-SOL (levothyroxine sodium) oral solution contains synthetic L-3,3',5,5'-tetraiodothyronine sodium salt [levothyroxine (T4) sodium]. Synthetic T4 is chemically identical to that produced in the human thyroid gland. Levothyroxine (T4) sodium has an empirical formula of C15H10I4NNaO4• x H2O (where x = 5), molecular weight of 798.86 g/mol (anhydrous), and structural formula as shown:
TIROSINT-SOL oral solution is a clear, colorless to slightly yellow solution supplied in a 1 mL white, non-transparent, unit-dose ampule and is available in the following strengths (mcg/mL): 13, 25, 50, 75, 88, 100, 112, 125, 137, 150, 175, 200.
The inactive ingredients in TIROSINT-SOL are glycerol and water.
Last reviewed on RxList: 3/8/2017
This monograph has been modified to include the generic and brand name in many instances.
Additional Tirosint-Sol Information
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