March 28, 2017
Recommended Topic Related To:

Tirosint-Sol

"DENVER ” New data shed more light on the specific risks of congenital birth defects associated with the Graves' disease drug methimazole (MMI) and the timing of the teratogenic effects.

The results indicate that there were significant"...

A A A

Tirosint-Sol

TIROSINT®-SOL
(levothyroxine sodium) Oral Solution

WARNING

NOT FOR TREATMENT OF OBESITY or FOR WEIGHT LOSS

Thyroid hormones, including TIROSINT-SOL, either alone or with other therapeutic agents, should not be used for the treatment of obesity or for weight loss.

In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction.

Larger doses may produce serious or even life threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects [see ADVERSE REACTIONS, DRUG INTERACTIONS, and OVERDOSAGE].

DRUG DESCRIPTION

TIROSINT-SOL (levothyroxine sodium) oral solution contains synthetic L-3,3',5,5'-tetraiodothyronine sodium salt [levothyroxine (T4) sodium]. Synthetic T4 is chemically identical to that produced in the human thyroid gland. Levothyroxine (T4) sodium has an empirical formula of C15H10I4NNaO4• x H2O (where x = 5), molecular weight of 798.86 g/mol (anhydrous), and structural formula as shown:

TIROSINT®-SOL (levothyroxine sodium) Structural Formula Illustration

TIROSINT-SOL oral solution is a clear, colorless to slightly yellow solution supplied in a 1 mL white, non-transparent, unit-dose ampule and is available in the following strengths (mcg/mL): 13, 25, 50, 75, 88, 100, 112, 125, 137, 150, 175, 200.

The inactive ingredients in TIROSINT-SOL are glycerol and water.

Last reviewed on RxList: 3/8/2017
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Women's Health

Find out what women really need.