"For children who have had HIV-1 infection since birth, the combination drug therapies now used to treat HIV appear to protect against the heart damage seen before combination therapies were available, according to researchers in a National Instit"...
Limited experience with single higher doses (up to 250 mg in healthy subjects) revealed no specific symptoms or signs apart from those listed as adverse reactions. There is no known specific treatment for overdose with TIVICAY. If overdose occurs, the patient should be monitored and standard supportive treatment applied as required. As dolutegravir is highly bound to plasma proteins, it is unlikely that it will be significantly removed by dialysis.
Coadministration of TIVICAY with dofetilide is contraindicated due to the potential for increased dofetilide plasma concentrations and the risk for serious and/or life-threatening events [see DRUG INTERACTIONS].
Last reviewed on RxList: 6/2/2014
This monograph has been modified to include the generic and brand name in many instances.
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