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Tobi

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Tobi




Overdosage
Contraindications

OVERDOSE

Signs and symptoms of acute toxicity from overdosage of intravenous (IV) tobramycin might include dizziness, tinnitus, vertigo, loss of high-tone hearing acuity, respiratory failure, neuromuscular blockade, and renal impairment. Administration by inhalation results in low systemic bioavailability of tobramycin. Tobramycin is not significantly absorbed following oral administration. Tobramycin serum concentrations may be helpful in monitoring overdosage.

In all cases of suspected overdosage, physicians should contact the Regional Poison Control Center for information about effective treatment. In the case of any overdosage, the possibility of drug interactions with alterations in drug disposition should be considered.

CONTRAINDICATIONS

TOBI is contraindicated in patients with a known hypersensitivity to any aminoglycoside.

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 10/19/2015

Overdosage
Contraindications

Tobi - User Reviews

Tobi User Reviews

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Here is a collection of user reviews for the medication Tobi sorted by most helpful. Patient Discussions FAQs

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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