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Tobradex Ointment

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Tobradex Ophthalmic Ointment

TobraDex®
(tobramycin and dexamethasone) Ophthalmic Ointment Sterile

DRUG DESCRIPTION

TOBRADEX® (tobramycin and dexamethasone ophthalmic ointment) is a sterile, multiple dose antibiotic and steroid combination for topical ophthalmic use. The chemical structures for tobramycin and dexamethasone are presented below:

TobraDex (tobramycin) structural formula illustration

Tobramycin

Empirical Formula: C18H37N5O9
Chemical name:
0-{-3-amino-3-deoxy-α-D-gluco-pyranosyl-(1→4)}-0-{2,6 diamino-2,3,6-trideoxy- α-D-ribohexo-pyranosol-(1→6)}-2-deoxy-L-streptamine.
MW = 467.52

TobraDex (dexamethasone) structural formula illustration

Dexamethasone

Empirical Formula: C22H29FO5
Chemical Name:
9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
MW = 392.47

Each gram of TOBRADEX® (tobramycin and dexamethasone opthalmic ointment) (tobramycin and dexamethasone ophthalmic ointment) contains: Actives: tobramycin 0.3% (3mg) and dexamethasone 0.1% (1 mg). Preservative: chlorobutanol 0.5%. Inactives: mineral oil and white petrolatum.

What are the possible side effects of tobramycin and dexamethasone ophthalmic (Tobradex)?

Serious side effects are not expected to occur with the use of this medication.

Some burning, stinging, irritation, itching, redness, blurred vision, eyelid itching, eyelid swelling, or sensitivity to light may occur.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at...

Read All Potential Side Effects and See Pictures of Tobradex Ophthalmic Ointment »

What are the precautions when taking tobramycin and dexamethasone opthalmic ointment (Tobradex Ophthalmic Ointment)?

Before using tobramycin with dexamethasone, tell your doctor or pharmacist if you are allergic to either drug; or to other aminoglycoside antibiotics (e.g., gentamicin); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: other eye problems (e.g., glaucoma).

Your vision may be temporarily blurred or unstable after applying this drug. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

This medication should be used only when clearly needed during pregnancy. Discuss...

Read All Potential Precautions of Tobradex Ophthalmic Ointment »

Last reviewed on RxList: 1/2/2008
This monograph has been modified to include the generic and brand name in many instances.

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Tobradex Ophthalmic Ointment - User Reviews

Tobradex Ophthalmic Ointment User Reviews

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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