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Tobradex

Last reviewed on RxList: 10/10/2016
Tobradex Side Effects Center

Last reviewed on RxList 10/5/2016

Tobradex (tobramycin and dexamethasone ophthalmic suspension) is a combination antibiotic and steroid used to treat bacterial infections of the eyes. Tobradex is available in generic form. Common side effects of Tobradex include:

  • eye redness,
  • discomfort,
  • burning,
  • stinging,
  • irritation,
  • itching;
  • eyelid itching/swelling,
  • blurred vision, or
  • sensitivity to light.
  • Use of Tobradex for prolonged/repeated periods may result in a new fungal eye infection and may increase your risk for other eye problems (e.g., glaucoma, cataracts).

One or two drops of Tobradex ophthalmic should be instilled into the conjunctival sac(s) every four to six hours. During the initial 24 to 48 hours, the dosage may be increased to one or two drops every two (2) hours. Do not use other eye drops or medications during treatment with Tobradex ophthalmic unless directed by your doctor. Tobradex may interact with oral steroid medications. Other drugs may interact with Tobradex ophthalmic. Tell your doctor all prescription or over-the-counter medicines or supplements you use. Tobradex should be used only when prescribed during pregnancy. It is not known if this medication passes into breast milk. Consult your doctor before breastfeeding.

Our Tobradex (tobramycin and dexamethasone ophthalmic suspension) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tobradex Consumer Information

Serious side effects are not expected to occur with the use of this medication.

Some burning, stinging, irritation, itching, redness, blurred vision, eyelid itching, eyelid swelling, or sensitivity to light may occur.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Tobradex (Tobramycin and Dexamethasone)

Tobradex Professional Information

SIDE EFFECTS

Adverse reactions have occurred with steroid/anti-infective combination drugs which can be attributed to the steroid component, the anti-infective component, or the combination. Exact incidence figures are not available. The most frequent adverse reactions to topical ocular tobramycin [TOBREX® (tobramycin ophthalmic solution)] are hypersensitivity and localized ocular toxicity, including lid itching and swelling, and conjunctival erythema. These reactions occur in less than 4% of patients. Similar reactions may occur with the topical use of other aminoglycoside antibiotics. Other adverse reactions have not been reported; however, if topical ocular tobramycin is administered concomitantly with systemic aminoglycoside antibiotics, care should be taken to monitor the total serum concentration. The reactions due to the steroid component are: elevation of intraocular pressure (IOP) with possible development of glaucoma, and infrequent optic nerve damage; posterior subcapsular cataract formation; and delayed wound healing.

Secondary Infection

The development of secondary infection has occurred after use of combinations containing steroids and antimicrobials. Fungal infections of the cornea are particularly prone to develop coincidentally with long-term applications of steroids. The possibility of fungal invasion must be considered in any persistent corneal ulceration where steroid treatment has been used. Secondary bacterial ocular infection following suppression of host responses also occurs.

Read the entire FDA prescribing information for Tobradex (Tobramycin and Dexamethasone)

Related Resources for Tobradex

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Read the Tobradex User Reviews »

© Tobradex Patient Information is supplied by Cerner Multum, Inc. and Tobradex Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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