"Jan. 22, 2013 -- Regular aspirin users are more likely to develop the "wet" form of age-related macular degeneration compared to people who rarely or never take the drug, a new study shows.
Aspirin is one of the most widely used drugs in th"...
As with other antibiotic preparations, prolonged use may result in overgrowth of nonsusceptible organisms, including fungi. If superinfection occurs, appropriate therapy should be initiated. Ophthalmic ointments may retard corneal wound healing. Cross-sensitivity to other aminoglycoside antibiotics may occur; if hypersensitivity develops with this product, discontinue use and institute appropriate therapy. Patients should be advised not to wear contact lenses if they have signs and symptoms of ocular infections.
Pregnancy Category B
Reproduction studies in three types of animals at doses up to thirty-three times the normal human systemic dose have revealed no evidence of impaired fertility or harm to the fetus due to tobramycin. There are, however, no adequate and well-controlled studies in pregnant women. Because animal studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.
Because of the potential for adverse reactions in nursing infants from TOBREX® (tobramycin ophthalmic ointment) 0.3 %, a decision should be made whether to discontinue nursing the infant or discontinue the drug, taking into account the importance of the drug to the mother.
Safety and effectiveness in pediatric patients below the age of 2 months has not been established.
No overall clinical differences in safety or effectiveness have been observed between the elderly and other adult patients.
Last reviewed on RxList: 3/26/2009
This monograph has been modified to include the generic and brand name in many instances.
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