"The U.S. Food and Drug Administration today approved Akynzeo (netupitant and palonosetron) to treat nausea and vomiting in patients undergoing cancer chemotherapy.
Akynzeo is a fixed combination capsule comprised of two drugs. Oral palonose"...
(Generic versions may still be available.)
Torecan Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Torecan (thiethylperazine maleate) is a phenothiazine used to relieve nausea and vomiting. The brand name of this medication is discontinued, but generic versions may be available. Common side effects include headache, dizziness, drowsiness, agitation, weakness, tremor (shaking), increased heart rate, constipation, or dry mouth.
The usual adult daily dose range of Torecan is 10 mg to 30 mg. Torecan may interact with other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, and muscle relaxants. Tell your doctor all medications and supplements you use. It is unknown if Torecan will be harmful to a fetus. Tell your doctor if you are pregnant or could become pregnant. It is unknown if this drug passes into breast milk and how it might affect a nursing infant. Consult your doctor before breastfeeding.
Our Torecan (thiethylperazine maleate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Torecan FDA Prescribing Information: Side Effects
Serious: Convulsions have been reported. Extrapyramidal symptoms (E.P.S.) may occur, such as dystonia, torticoilis, oculogyric crises, akathisia and gait disturbances. Others: Occasional cases of dizziness, headache, fever and restlessness have been reported.
Drowsiness may occur on occasion, following an initial injection. Generally this effect tends to subside with continued therapy or is usually alleviated by a reduction in dosage.
An occasional case of cholestatic jaundice has been observed.
The physician should be aware that the following have occurred with one or more phenothiazines and should be considered whenever one of these drugs is used:
Extrapyramidal Symptoms: Serious - Akathisia, agitation, motor restlessness, dystonic reactions, trismus, torticollis, opisthotonos, oculogyric crises, tremor, muscular rigidity, akinesia - some of which have persisted for several months or years especially in patients of advanced age with brain damage.
Others: Hyperpyrexia. Behavioral effects suggestive of a paradoxical reaction have been reported. These include excitement, bizarre dreams, aggravation of psychoses and toxic confusional states. While there is no evidence at present that ECG changes observed in patients receiving phenothiazines are in any way precursors of any significant disturbance of cardiac rhythm, it should be noted that sudden and unexpected deaths apparently due to cardiac arrest have been reported in a few instances in hospitalized psychotic patients previously showing characteristic ECG changes. A peculiar skin-eye syndrome has also been recognized as a side effect following long-term treatment with certain phenothiazines. This reaction is marked by progressive pigmentation of areas of the skin or conjunctiva and/or accompanied by discoloration of the exposed sclera and cornea. Opacities of the anterior lens and cornea described as irregular or stellate in shape have also been reported.
DRUG ABUSE AND DEPENDENCE
TORECAN (thiethylperazine) is not a controlled substance.
Read the entire FDA prescribing information for Torecan (Thiethylperazine)
Additional Torecan Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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