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Torisel

The kidneys

The kidneys are a pair of organs on either side of the spine in the lower abdomen. Each kidney is about the size of a fist. Attached to the top of each kidney is an adrenal gland. A mass of fatty tissue and an outer layer of fibrous tissue (Gerota's fascia) enclose the kidneys and adrenal glands.

The kidneys are part of the urinary tract. They make urine by removing wastes and extra water from the blood. Urine collects in a hollow space (renal pelvis) in the middle of each kidney. It passes from the renal pelvis into the bladder through a tube called a ureter. Urine leaves the body through another tube (the urethra).

The kidneys also make substances that help control blood pressure and the production of red blood cells.

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Torisel

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OVERDOSE

There is no specific treatment for TORISEL (temsirolimus injection) intravenous overdose. TORISEL (temsirolimus injection) has been administered to patients with cancer in phase 1 and 2 trials with repeated intravenous doses as high as 220 mg/m². The risk of several serious adverse events, including thrombosis, bowel perforation, interstitial lung disease (ILD), seizure, and psychosis, is increased with doses of TORISEL (temsirolimus injection) greater than 25 mg.

CONTRAINDICATIONS

TORISEL (temsirolimus injection) is contraindicated in patients with bilirubin > 1.5 x ULN [see WARNINGS AND PRECAUTIONS].

Last reviewed on RxList: 8/5/2010
This monograph has been modified to include the generic and brand name in many instances.

Torisel - User Reviews

Torisel User Reviews

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