Tracleer (Bosentan) Drug Overview and Uses for Patients and Caregivers at RxList

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May 27, 2012

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High Blood Pressure »

High blood pressure facts

High blood pressure (hypertension) is designated as either essential (primary) hypertension or secondary hypertension and is defined as a consistently elevated blood pressure exceeding 140/90 mm Hg.
High blood pressure is called "the silent killer" because it often causes no symptoms for many years, even decades, until it finally damages certain critical organs.
Poorly controlled high blood pressure ultimately can cause damage to blood vessels in the eye, thickening of the heart muscle and heart attacks, hardening of the arteries (arteriosclerosis), kidney failure, and strokes.
Most antihypertensive medications can be used alone or in combination. Some are used only in combination. Some are preferred over others in certain specific medical situations. And some are not to be used (contraindicated) in other situations.
Several classes of antihypertensive medications are available, including ACE i...

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Tracleer Consumer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

BOSENTAN - ORAL

(boe-SEN-tan)

COMMON BRAND NAME(S): Tracleer

WARNING: Bosentan has rarely caused very serious liver problems. Your doctor will monitor your liver function blood tests monthly. Tell your doctor immediately if you develop symptoms of liver disease, including persistent nausea/vomiting, stomach/abdominal pain, extreme tiredness, dark urine, yellowing eyes/skin.

This medication must not be used during pregnancy because it can cause harm to a fetus/unborn baby. See also Precautions section.

USES: Bosentan is used to treat high blood pressure in the lungs (pulmonary arterial hypertension). This condition is thought to be caused by increased levels of a certain natural substance (endothelin-1). This medication blocks the effects of endothelin-1, thereby helping to decrease the blood pressure in the lungs, slow the worsening of symptoms from the disease, and improve your ability to exercise.

HOW TO USE: This drug is controlled through a special program. Someone will call you each month to remind you to have your liver function test (and pregnancy test for women of child-bearing age). See also Warning and Precautions sections.

Read the Medication Guide provided by your pharmacist before you start using bosentan and each time you get a refill. If you have any questions, consult your doctor or pharmacist.

Take this medication by mouth with or without food, usually twice daily (in the morning and evening) or as directed by your doctor.

Dosage is based on your medical condition, weight, and response to treatment. Your doctor will usually start you on a lower dose of this medication and then increase the dose after several weeks.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day.

Do not stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.

Women who are pregnant or who may become pregnant should not handle the tablets or breathe the dust from this medication. Do not crush the tablets because doing so will increase exposure to the dust.

Tell your doctor if your condition persists or worsens.