"The U.S. Food and Drug Administration today approved Invokana (canagliflozin) tablets, used with diet and exercise, to improve glycemic control in adults with type 2 diabetes.
Type 2 diabetes is the most common form of the disease, affe"...
- Clinician Information:
Tradjenta Patient Information including If I Miss a Dose
In this Article
- What is linagliptin (Tradjenta)?
- What are the possible side effects of linagliptin (Tradjenta)?
- What is the most important information I should know about linagliptin (Tradjenta)?
- What should I discuss with my healthcare provider before taking linagliptin (Tradjenta)?
- How should I take linagliptin (Tradjenta)?
- What happens if I miss a dose (Tradjenta)?
- What happens if I overdose (Tradjenta)?
- What should I avoid while taking linagliptin (Tradjenta)?
- What other drugs will affect linagliptin (Tradjenta)?
- Where can I get more information?
What happens if I miss a dose (Tradjenta)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Tradjenta)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
You may have signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).
What should I avoid while taking linagliptin (Tradjenta)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.
What other drugs will affect linagliptin (Tradjenta)?
Tell your doctor about all other medicines you use, especially:
- bosentan (Tracleer);
- dexamethasone (Cortastat, Dexasone, Solurex, DexPak);
- ketoconazole (Nizoral);
- quinidine (Quin-G);
- rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin);
- St. John's wort;
- verapamil (Calan, Covera, Isoptin, Verelan);
- a barbiturate such as butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal), or phenobarbital (Solfoton);
- HIV/AIDS medication such as efavirenz (Sustiva, Atripla), etravirine (Intelence), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, Kaletra), or saquinavir (Invirase);
- medicines to treat narcolepsy, such as armodafanil (Nuvigil) or modafanil (Progivil);
- medicines used to prevent organ transplant rejection, such as cyclosporine (Gengraf, Neoral, Sandimmune) or tacrolimus (Prograf); or
- seizure medication such as carbamazepine (Carbatrol, Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), phenytoin (Dilantin), or primidone (Mysoline).
Although linagliptin is not as likely to cause hypoglycemia (low blood sugar) as some other oral diabetes medications, tell your doctor if you are taking any other drugs that can potentially lower blood sugar, such as:
- probenecid (Benemid);
- nonsteroidal anti-inflammatory drugs (NSAIDs);
- aspirin or other salicylates (including Pepto-Bismol);
- sulfa drugs (Bactrim and others);
- a monoamine oxidase inhibitor (MAOI);
- another oral diabetes medication such as glipizide (Glucotrol, Metaglip), glimepiride (Amaryl, Avandaryl, Duetact), glyburide (DiaBeta, Micronase, Glucovance), and others.
- beta-blockers (Tenormin and others); or
This list is not complete and other drugs may interact with linagliptin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about linagliptin.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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Additional Tradjenta Information
- Tradjenta Drug Interactions Center: linagliptin oral
- Tradjenta Side Effects Center
- Tradjenta FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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