Brand Names: Normodyne, Trandate

Generic Name: labetalol (Pronunciation: la BAY ta lol)

• What is labetalol (Trandate)?
• What are the possible side effects of labetalol (Trandate)?
• What is the most important information I should know about labetalol (Trandate)?
• What should I discuss with my healthcare provider before taking labetalol (Trandate)?
• How should I take labetalol (Trandate)?
• What happens if I miss a dose (Trandate)?
• What happens if I overdose (Trandate)?
• What should I avoid while taking labetalol (Trandate)?
• What other drugs will affect labetalol (Trandate)?
• Where can I get more information?

What is labetalol (Trandate)?

Labetalol is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

Labetalol is used to treat hypertension (high blood pressure).

Labetalol may also be used for purposes other than those listed in this medication guide.

Labetalol 100 mg-EON

round, white, imprinted with E 10

Labetalol 100 mg-IVA

round, yellow, imprinted with 100, LOGO 4364

Labetalol 100 mg-WAT

round, beige, imprinted with WATSON 605

Labetalol 200 mg-EON

round, white, imprinted with E117

Labetalol 200 mg-IVA

round, white, imprinted with LOGO 4365, 200

Labetalol 200 mg-WAT

round, white, imprinted with WATSON 606

Labetalol 300 mg-EON

round, white, imprinted with E 118

Labetalol 300 mg-IVA

round, green, imprinted with 300, LOGO 4366

Labetalol 300 mg-WAT

round, blue, imprinted with WATSON 607

What are the possible side effects of labetalol (Trandate)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• slow or uneven heartbeats;
• feeling light-headed, fainting;
• feeling short of breath, even with mild exertion;
• swelling of your ankles or feet;
• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
• depression; or
• cold feeling in your hands and feet.

Other less serious side effects are more likely to occur, such as:

• decreased sex drive, impotence, or difficulty having an orgasm;
• sleep problems (insomnia);
• tired feeling; or
• anxiety, nervousness.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about labetalol (Trandate)?

Do not stop taking labetalol without first talking to your doctor. Stopping suddenly may make your condition worse.

If you need to have any type of surgery, you may need to temporarily stop using labetalol. Be sure the surgeon knows ahead of time that you are using labetalol.

Labetalol can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking labetalol.

Labetalol is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.

Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.