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Tranxene Side Effects Center
Pharmacy Editor: Charles Patrick Davis, MD, PhD
Tranxene (clorazepate dipotassium) is a benzodiazepine used to treat anxiety, seizure disorders, and alcohol withdrawal symptoms. Tranxene is available in a generic form termed clorazepate. Common side effects of Tranxene include dizziness, drowsiness, tiredness, blurred vision, sleep problems (insomnia), nausea, vomiting, stomach pain, constipation, dry mouth, headache, amnesia or forgetfulness, muscle weakness, lack of balance or coordination, nervousness, irritability, or skin rash.
Tranxene (clorazepate dipotassium) is available in strengths of 3.75, 7.5 and 15 mg tablets. The starting dose is usually 30mg but may vary according to the type of problem treated; doctors should prescribe the dose. Serious side effects include confusion, depression, suicide ideation, muscle tremors, dependence and urinary problems. Pregnant or breast-feeding women should either stop or do not start using Tranxene due to potential harm to the fetus or infant. The drug is not recommended for use in patients less than 9 years of age.
Our Tranxene Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Tranxene in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- confusion, unusual thoughts or behavior;
- depressed mood, thoughts of suicide or hurting yourself;
- muscle twitching, tremor; or
- problems with urination.
Less serious side effects may include:
- drowsiness, tiredness;
- amnesia or forgetfulness;
- blurred vision;
- feeling nervous or irritable;
- sleep problems (insomnia);
- muscle weakness, lack of balance or coordination;
- skin rash;
- nausea, vomiting, stomach pain, constipation; or
- dry mouth; or
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Tranxene (Clorazepate Dipotassium)
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Tranxene Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: slurred speech, clumsiness, trouble walking, decreased/increased interest in sex, tremor, trouble urinating, sleep disturbances.
A small number of people who take anticonvulsants for any condition (such as seizure, bipolar disorder, pain) may experience depression, suicidal thoughts/attempts, or other mental/mood problems. Tell your doctor immediately if you or your family/caregiver notice any unusual/sudden changes in your mood, thoughts, or behavior including signs of depression, suicidal thoughts/attempts, thoughts about harming yourself.
Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: stomach/abdominal pain, persistent nausea, vomiting, yellowing eyes or skin, dark urine, persistent sore throat or fever.
A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Tranxene (Clorazepate Dipotassium)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Tranxene FDA Prescribing Information: Side Effects
The side effect most frequently reported was drowsiness. Less commonly reported (in descending order of occurrence) were: dizziness, various gastrointestinal complaints, nervousness, blurred vision, dry mouth, headache, and mental confusion. Other side effects included insomnia, transient skin rashes, fatigue, ataxia, genitourinary complaints, irritability, diplopia, depression, tremor, and slurred speech.
There have been reports of abnormal liver and kidney function tests and of decrease in hematocrit.
Decrease in systolic blood pressure has been observed.
To report SUSPECTED ADVERSE REACTIONS, contact Recordati Rare Diseases Inc. at 1-888-575-8344 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.
Read the entire FDA prescribing information for Tranxene (Clorazepate Dipotassium)
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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