IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

BENDAMUSTINE - INJECTION

(BEN-da-MUS-teen)

COMMON BRAND NAME(S): Treanda

USES: This medication is used to treat certain types of cancer (e.g., chronic lymphocytic leukemia-CLL, B-cell non-Hodgkin's lymphoma). Bendamustine belongs to a class of cancer chemotherapy drugs known as alkylating agents. It works by killing cancer cells or slowing their growth.

HOW TO USE: This medication is injected slowly into a vein by a health care professional as directed by your doctor.

The dosage is based on your medical condition, body size, and response to treatment. Before each cycle, you should have blood tests to find the best dose for you and to see whether you need to wait before receiving this drug again.

Before you receive this medication, your doctor may direct you to take a fever reducer, an antihistamine, and a corticosteroid such as dexamethasone to help prevent side effects. Use these additional medications exactly as directed by your doctor. (See also Side Effects section.)

If bendamustine leaks out of the vein into the surrounding area, it may cause serious skin and tissue damage. Tell your health care professional immediately if you experience pain, irritation, redness, or swelling at the injection site. Prompt treatment of the leakage will help reduce discomfort and possible skin damage.