Treanda (Bendamustine Hydrochloride Injection) Patient Information: How Should I Take the Drug at RxList

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May 27, 2012

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Leukemia »

Leukemia facts

Leukemia is a cancer of the blood cells.
While the exact cause(s) of leukemia is not known, risk factors have been identified.
Leukemias are grouped by how quickly the disease develops (acute or chronic) as well as by the type of blood cell that is affected (lymphocytes or myelocytes). The four main types of leukemia include acute lymphocytic leukemia (ALL), chronic lymphocytic leukemia (CLL), acute myelocytic leukemia (AML), and chronic myelocytic leukemia (CML).
People with leukemia are at significantly increased risk for developing infections, anemia, and bleeding. Other symptoms and signs include easy bruising, weight loss, night sweats, and unexplained fevers.
The diagnosis of leukemia is supported by findings of the medical history and examination, and examining blood and bone marrow samples under a microscope.
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Treanda Patient Information including How Should I Take

What should I discuss with my healthcare provider before I receive bendamustine (Treanda)?

You should not receive this medication if you are allergic to bendamustine or mannitol (Osmitrol).

If you have any of these other conditions, you may need a dose adjustment or special tests to safely receive bendamustine:

a weak immune system;
fever or other signs of infection;
a metabolic disorder or electrolyte imbalance;
liver disease;
kidney disease; or
if you smoke.

FDA pregnancy category D. This medication can cause harm to an unborn baby. Before you receive bendamustine, tell your doctor if you are pregnant. Use effective birth control, and tell your doctor if you become pregnant during treatment.

It is not known whether bendamustine passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

Some people receiving bendamustine have developed certain types of cancers. It is not known whether this medication causes cancer. Talk with your doctor about the risks and benefits of using bendamustine.

How is bendamustine given (Treanda)?

Bendamustine is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting. The medicine must be given slowly through an IV infusion, and can take at least 30 minutes to complete.

Bendamustine is usually given for 2 days in a row every 21 to 28 days. You may receive up to 8 treatments total, depending on the condition being treated. Follow your doctor's instructions.

You may be given other medications to help prevent certain side effects of bendamustine.

To be sure this medication is not causing harmful effects, your blood may need to be tested on a regular basis. Your blood pressure may also need to be checked. Do not miss any scheduled appointments.

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