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Trecator Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Trecator (ethionamide) is used to treat tuberculosis (TB). It is an antibiotic. Common side effects include nausea, vomiting, diarrhea, abdominal/stomach pain, increased saliva, strange metallic taste in the mouth, loss of appetite, or sores in the mouth.
The usual adult dose of Trecator is 15 to 20 mg/kg/day, administered once daily or, if patient exhibits poor gastrointestinal tolerance, in divided doses, with a maximum daily dosage of 1 gram. Trecator may interact with cycloserine or isoniazid. Tell your doctor all medications and supplements you use. Trecator is not recommended for use during pregnancy. It may harm a fetus. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.
Our Trecator (ethionamide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Trecator in Detail - Patient Information: Side Effects
If you experience any of the following serious side effects, stop taking ethionamide and seek emergency medical attention:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
- yellow skin or eyes;
- dark urine;
- numbness or tingling in your hands or feet;
- blurred or double vision; or
- confusion or abnormal behavior.
Other, less serious side effects may be more likely to occur. Continue to take ethionamide and talk to your doctor if you experience
- nausea, vomiting, or loss of appetite;
- a metallic taste in your mouth;
- excessive salivation;
- unusual fatigue or weakness;
- mild dizziness;
- tremors (shaking); or
- a rash.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Trecator (Ethionamide Tablets)
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Trecator Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication may develop serious side effects, but with frequent visits to your doctor, this risk can be minimized.
Tell your doctor immediately if any of these unlikely but serious side effects occur: unusual hunger, unusual sweating, shakiness, persistent nausea/vomiting, unusual tiredness/weakness, yellowing eyes/skin, dark urine, joint pain/swelling, slow heartbeat, mental/mood changes (such as nervousness, restlessness, depression).
Tell your doctor immediately if any of these rare but serious side effects occur: vision changes (such as blurred/decreased/double vision, color blindness), eye pain, numbness/tingling of arms/legs.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Trecator (Ethionamide Tablets)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Trecator FDA Prescribing Information: Side Effects
Gastrointestinal: The most common side effects of ethionamide are gastrointestinal disturbances including nausea, vomiting, diarrhea, abdominal pain, excessive salivation, metallic taste, stomatitis, anorexia and weight loss. Adverse gastrointestinal effects appear to be dose related, with approximately 50% of patients unable to tolerate 1 gm as a single dose. Gastrointestinal effects may be minimized by decreasing dosage, by changing the time of drug administration, or by the concurrent administration of an antiemetic agent.
Nervous System: Psychotic disturbances (including mental depression), drowsiness, dizziness, restlessness, headache, and postural hypotension have been reported with ethionamide. Rare reports of peripheral neuritis, optic neuritis, diplopia, blurred vision, and a pellagra-like syndrome also have been reported. Concurrent administration of pyridoxine has been recommended to prevent or relieve neurotoxic effects.
Other: Hypersensitivity reactions including rash, photosensitivity, thrombocytopenia and purpura have been reported rarely. Hypoglycemia, hypothyroidism, gynecomastia, impotence, and acne also have occurred. The management of patients with diabetes mellitus may become more difficult in those receiving ethionamide.
Read the entire FDA prescribing information for Trecator (Ethionamide Tablets)
Additional Trecator Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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