Slideshows Images Quizzes

Trecator

Last reviewed on RxList: 9/8/2016
Trecator Side Effects Center

Last reviewed on RxList 4/12/2016

Trecator (ethionamide) is an antibiotic used to treat tuberculosis (TB). Common side effects of Trecator include:

The usual adult dose of Trecator is 15 to 20 mg/kg/day, administered once daily or, if patient exhibits poor gastrointestinal tolerance, in divided doses, with a maximum daily dosage of 1 gram. Trecator may interact with cycloserine or isoniazid. Tell your doctor all medications and supplements you use. Trecator is not recommended for use during pregnancy. It may harm a fetus. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Our Trecator (ethionamide) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Trecator Consumer Information

If you experience any of the following serious side effects, stop taking ethionamide and seek emergency medical attention:

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
  • yellow skin or eyes;
  • dark urine;
  • numbness or tingling in your hands or feet;
  • seizures;
  • blurred or double vision; or
  • confusion or abnormal behavior.

Other, less serious side effects may be more likely to occur. Continue to take ethionamide and talk to your doctor if you experience

  • nausea, vomiting, or loss of appetite;
  • a metallic taste in your mouth;
  • excessive salivation;
  • diarrhea;
  • unusual fatigue or weakness;
  • headache;
  • mild dizziness;
  • tremors (shaking); or
  • a rash.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Trecator (Ethionamide Tablets)

Trecator Professional Information

SIDE EFFECTS

Gastrointestinal

The most common side effects of ethionamide are gastrointestinal disturbances including nausea, vomiting, diarrhea, abdominal pain, excessive salivation, metallic taste, stomatitis, anorexia and weight loss. Adverse gastrointestinal effects appear to be dose related, with approximately 50% of patients unable to tolerate 1 gm as a single dose. Gastrointestinal effects may be minimized by decreasing dosage, by changing the time of drug administration, or by the concurrent administration of an antiemetic agent.

Nervous System

Psychotic disturbances (including mental depression), drowsiness, dizziness, restlessness, headache, and postural hypotension have been reported with ethionamide. Rare reports of peripheral neuritis, optic neuritis, diplopia, blurred vision, and a pellagra-like syndrome also have been reported. Concurrent administration of pyridoxine has been recommended to prevent or relieve neurotoxic effects.

Hepatic

Transient increases in serum bilirubin, SGOT, SGPT; Hepatitis (with or without jaundice).

Other

Hypersensitivity reactions including rash, photosensitivity, thrombocytopenia and purpura have been reported rarely. Hypoglycemia, hypothyroidism, gynecomastia, impotence, and acne also have occurred. The management of patients with diabetes mellitus may become more difficult in those receiving ethionamide.

Read the entire FDA prescribing information for Trecator (Ethionamide Tablets)

Related Resources for Trecator

Related Drugs

© Trecator Patient Information is supplied by Cerner Multum, Inc. and Trecator Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

Health Solutions From Our Sponsors