Trelstar Depot (Triptorelin pamoate) Patient Information: How Should I Take the Drug at RxList

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May 27, 2012

Trelstar Depot

Prostate Cancer »

What is the prostate gland?

The prostate gland is an organ that is located at the base or outlet (neck) of the urinary bladder. (See the diagram that follows.) The gland surrounds the first part of the urethra. The urethra is the passage through which urine drains from the bladder to exit from the penis. One function of the prostate gland is to help control urination by pressing directly against the part of the urethra that it surrounds. The main function of the prostate gland is to produce some of the substances that are found in normal semen, such as minerals and sugar. Semen is the fluid that transports the sperm to assist with reproduction. A man can manage quite well, however, without his prostate gland. (See the section on surgical treatment for prostate cancer.)

In a young man, the normal prostate gland is the size of a walnut (<30g). During normal aging, however, the gland usually grows larger. This hormone-related enlargement with aging is called b...

Read the Prostate Cancer article »

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Trelstar Depot Patient Information including How Should I Take

What should I discuss with my healthcare provider before using triptorelin (Trelstar Depot)?

Do not use triptorelin without first talking to your doctor if you are allergic to luteinizing hormone releasing hormone (LHRH) or other similar drugs such as leuprolide (Lupron, Viadur, Eligard) or goserelin (Zoladex) . You may not be able to use triptorelin or you may require special monitoring during treatment.

Before using triptorelin, tell your doctor if you have

metastatic back bone (spinal) lesions, or
a urinary tract obstruction.

You may not be able to use triptorelin, or you may require a dosage adjustment or special monitoring during treatment.

Triptorelin is in the FDA pregnancy category X. This means that triptorelin will cause birth defects in an unborn baby. Do not use this medication if you are pregnant or if you could become pregnant during treatment.

It is not known whether triptorelin passes into breast milk. Do not use this medication without first talking to your doctor if you are breast-feeding a baby.

How should I use triptorelin (Trelstar Depot)?

Triptorelin must be administered under the supervision of a physician.

Triptorelin is injected into the muscle, usually once a month.

Your doctor or nurse will rotate the site of the injection periodically.

Triptorelin initially causes a temporary increase in serum testosterone levels. Because of this, symptoms of prostate cancer may worsen during the first weeks of treatment. Notify your doctor if you experience new or worsening symptoms such as bone pain; blood in the urine; difficulty urinating; or numbness, tingling, weakness, or paralysis.

Triptorelin vials for injection should be stored at room temperature away from moisture and heat.

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