"In men with prostate cancer, regular aspirin use is associated with a slower rate of disease progression and a reduced risk of dying from the disease, according to a new study.
The findings come from an analysis of data from the large"...
(triptorelin pamoate) for Injectable Suspension
TRELSTAR is a white to slightly yellow lyophilized cake. When reconstituted, TRELSTAR has a milky appearance. It contains a pamoate salt of triptorelin, a synthetic decapeptide agonist analog of gonadotropin releasing hormone (GnRH). The chemical name of triptorelin pamoate is 5-oxo-L-prolyl- L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolylglycine amide (pamoate salt). The empirical formula is C64H82N18O13 • C23H16O6 and the molecular weight is 1699.9. The structural formula is:
The TRELSTAR products are sterile, lyophilized biodegradable microgranule formulations supplied as single dose vials. Refer to Table 5 for the composition of each TRELSTAR product.
Table 5: TRELSTAR Composition
|Ingredients||TRELSTAR 3.75 mg||TRELSTAR 11.25 mg||TRELSTAR 22.5 mg|
|triptorelin pamoate (base units)||3.75 mg||11.25 mg||22.5 mg|
|poly-d,l-lactide-co-glycolide||136 mg||118 mg||182 mg|
|mannitol, USP||69 mg||76 mg||68 mg|
|carboxymethylcellulose sodium, USP||24 mg||27 mg||24 mg|
|polysorbate 80, NF||1.6 mg||1.8 mg||1.6 mg|
When 2 mL sterile water is added to the vial containing TRELSTAR and mixed, a suspension is formed which is intended as an intramuscular injection. TRELSTAR is available in two packaging configurations: (a) TRELSTAR vial alone or (b) TRELSTAR vial plus a MIXJECT vial adapter, and a separate pre-filled syringe that contains sterile water for injection, USP, 2 mL, pH 6 to 8.5.
Last reviewed on RxList: 11/24/2014
This monograph has been modified to include the generic and brand name in many instances.
Additional Trelstar Information
- Trelstar Drug Interactions Center: triptorelin pamoate im
- Trelstar Side Effects Center
- Trelstar FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Get the latest treatment options.