Trental (Pentoxifylline) Drug Center: Guide to Drug Information for Professionals, Patients and Caregivers at RxList

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May 27, 2012

Trental

Sickle Cell Disease (Sickle Cell Anemia) »

What is sickle cell anemia?

Sickle cell anemia (sickle cell disease) is a disorder of the blood caused by an inherited abnormal hemoglobin (an oxygen-carrying protein within the red blood cells). The abnormal hemoglobin causes distorted (sickled) red blood cells. The sickled red blood cells are fragile and prone to rupture. When the number of red blood cells decreases from rupture (hemolysis), anemia is the result. This condition is referred to as sickle cell anemia. The irregular sickled cells can also block blood vessels causing tissue and organ damage and pain.

Sickle cell anemia is one of the most common inherited blood anemias. The disease primarily affects Africans and African Americans. It is estimated that in the United States, some 50,000 African Americans are afflicted with the most severe form of sickle cell anemia. Overall, current estimates are that one in 1,875 U.S. African American is affected with sickle cell anemia./...

Read the Sickle Cell Disease (Sickle Cell Anemia) article »

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Trental User Reviews >>

Trental

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Trental Drug Center

Medical Editor: John P. Cunha, DO, FACOEP

Prescribing Information

For Patients

Trental (pentoxifylline) is used to improve blood flow. Improved blood flow helps reduce leg cramps and other symptoms of vascular disease (disease related to veins and arteries). It is a hemorrheologic agent (an agent that affects blood viscosity). This medication is available in generic form. Common side effects include nausea, vomiting, gas, belching, and dizziness.

The usual dosage of Trental in extended-release tablet form is one tablet (400 mg) three times a day with meals. It is recommended treatment is continued for at least 8 weeks. Trental may interact with blood thinners, theophylline, aminophylline, dyphylline, and oxtriphylline. Tobacco may worsen your condition or decrease the beneficial effects of Trental by narrowing your blood vessels. Talk to your doctor if you use tobacco. Tell your doctor all medications you use. During pregnancy, Trental should be used only when prescribed. This medication passes into breast milk. Consult your doctor before breast-feeding.

Our Trental (pentoxifylline) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Trental Prescribing Information: Indications & Dosage

TRENTAL®
(pentoxifylline) Structural Formula Illustration

TRENTAL (pentoxifylline) is indicated for the treatment of patients with intermittent claudication on the basis of chronic occlusive arterial disease of the limbs. TRENTAL (pentoxifylline) can improve function and symptoms but is not intended to replace more definitive therapy, such as surgical bypass, or removal of arterial obstructions when treating peripheral vascular disease.

Read the complete drug monograph for Trental »

What is Trental Prescribing Information?

Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Trental Patient Information: Side Effects

If you experience any of the following serious side effects, stop taking pentoxifylline and seek medical attention:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
chest pain or an irregular heartbeat;
severe dizziness, headache, nosebleeds, or blurred vision;
nausea or vomiting; or
swollen feet or ankles.

Other, less serious side effects may be more likely to occur. Continue to take pentoxifylline and talk to your doctor if you experience/...

Read the complete patient information for Trental »

What is Trental Patient Information?

Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Trental Consumer Information: Uses

This medication is used to improve the symptoms of a certain blood flow problem in the legs/arms (intermittent claudication due to occlusive artery disease). Pentoxifylline can decrease the muscle aching/pain/cramps during exercise, including walking, that occur with intermittent claudication. Pentoxifylline belongs to a class of drugs known as hemorrheologic agents. It works by helping blood flow more easily through narrowed arteries. This increases the amount of oxygen that can be delivered by the blood when the muscles need more (such as during exercise) thereby increasing walking distance ...

Read the complete consumer information for Trental »