Trental (Pentoxifylline) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

Pill Identifier Search

February 3, 2012

Trental

Raynaud's Phenomenon »

What is Raynaud's phenomenon?

Raynaud's phenomenon (RP) is a condition resulting in a particular series of discolorations of the fingers and/or the toes after exposure to changes in temperature (cold or hot) or emotional events. Skin discoloration occurs because an abnormal spasm of the blood vessels causes a diminished blood supply to the local tissues. Initially, the digit(s) involved turn white because of the diminished blood supply. The digit(s) then turn blue because of prolonged lack of oxygen. Finally, the blood vessels reopen, causing a local "flushing" phenomenon, which turns the digit(s) red. This three-phase color sequence (white to blue to red), most often upon exposure to cold temperature, is characteristic of RP.

Raynaud's phenomenon most frequently affects women, especially in the second, third, or fourth decades of life. People can have Raynauds phenomenon alone or as a part of other rheumatic diseases. When it occurs alone...

Read the Raynaud's Phenomenon article »

« Previous
1
2
3
4
5
6
7
8
9
10
11
12
13
next »

Trental User Reviews >>

Trental

font size

TRENTAL®
(pentoxifylline) Tablets, 400 mg

DRUG DESCRIPTION

TRENTAL® (pentoxifylline) tablets for oral administration contain 400 mg of the active drug and the following inactive ingredients: FD&C Red No. 3, hypromellose USP, magnesium stearate NF, polyethylene glycol NF, povidone USP, talc USP, titanium dioxide USP, and hydroxyethyl cellulose USP in an extended-release formulation. TRENTAL (pentoxifylline) is a tri-substituted xanthine derivative designated chemically as 1-(5-oxohexyl)-3, 7-dimethylxanthine that, unlike theophylline, is a hemorrheologic agent, i.e. an agent that affects blood viscosity. Pentoxifylline is soluble in water and ethanol, and sparingly soluble in toluene. The CAS Registry Number is 6493-05-6.

The chemical structure is:

TRENTAL®
(pentoxifylline) Structural Formula Illustration

What are the possible side effects of pentoxifylline (Pentoxil, Trental)?

If you experience any of the following serious side effects, stop taking pentoxifylline and seek medical attention:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
chest pain or an irregular heartbeat;
severe dizziness, headache, nosebleeds, or blurred vision;
nausea or vomiting; or
swollen feet or ankles.

Other, less serious side effects may be more likely to occur. Continue to take...

Read All Potential Side Effects and See Pictures of Trental »

What are the precautions when taking pentoxifylline (Trental)?

Before taking pentoxifylline, tell your doctor or pharmacist if you are allergic to it; or to caffeine, or theophylline; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: recent stroke, recent bleeding in the eye, kidney problems, recent major surgery, stomach ulcer.

This drug may rarely make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

Before having surgery, tell your doctor or dentist about all the products you use...

Read All Potential Precautions of Trental »

Last reviewed on RxList: 3/16/2009
This monograph has been modified to include the generic and brand name in many instances.