Proper name: pentoxifylline
Chemical name: 3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione
Molecular formula: C13H18N4O3
Molecular mass: 278.3
Pentoxifylline is a white to creamy white, crystalline powder. It is freely soluble in chloroform and methanol, soluble in water, sparingly soluble in ethanol and slightly soluble in ether. It has a melting point of 104°C to 107°C, within a 3°C range.
What are the possible side effects of pentoxifylline (Pentoxil, Trental)?
If you experience any of the following serious side effects, stop taking pentoxifylline and seek medical attention:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
- chest pain or an irregular heartbeat;
- severe dizziness, headache, nosebleeds, or blurred vision;
- nausea or vomiting; or
- swollen feet or ankles.
Other, less serious side effects may be more likely to occur. Continue to take pentoxifylline and talk to your doctor if you...
What are the precautions when taking pentoxifylline (Trental)?
Before taking pentoxifylline, tell your doctor or pharmacist if you are allergic to it; or to caffeine, or theophylline; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: recent stroke, recent bleeding in the eye, kidney problems, recent major surgery, stomach ulcer.
This drug may rarely make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.
Before having surgery, tell your doctor or dentist about all the products you use...
Last reviewed on RxList: 7/16/2012
This monograph has been modified to include the generic and brand name in many instances.
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