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Trexall
What is liver disease?
Liver disease is any disturbance of liver function that causes illness. The liver is responsible for many critical functions within the body and should it become diseased or injured, the loss of those functions can cause significant damage to the body. Liver disease is also referred to as hepatic disease.
Liver disease is a broad term that covers all the potential problems that may occur to cause the liver to fail to perform its designated functions. Usually, more than 75% or three quarters of liver tissue needs to be affected before decrease in function occurs.
The liver the largest solid organ in the body; and is also considered a gland because among its many functions, it makes and secretes bile. The liver is located in the upper right portion of the abdomen protected by the rib cage. It has two main lobes that are made up of tiny lobules. The liver cells have two different sources of blood supply. The hepatic ...
Trexall
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Trexall Drug Center
Medical Editor: Charles Patrick Davis, MD, PhD
Trexall (methotrexate) is an antimetabolite drug that is used to treat some cancers, severe skin diseases such as severe psoriasis, and to treat forms of rheumatoid arthritis. Its generic form is termed methotrexate. The drug, by interfering with folate metabolism, ultimately compromises nucleic acid production and tissue cell reproduction. Mild to moderate side effects of Trexall may include stomatitis, nausea, abdominal pain, and leukopenia (low number of white cells in blood), but the drug also has many other severe side effects (see below); patients need to strictly follow prescribed doses and secure this drug from child access.
Trexall is supplied in 5, 7.5, 10, and 15 mg tablets. The dose is designed for each patient's problem and can range from about 7.5 mg per week to 30 mg per day, depending on the disease process and the doctor's judgment. This drug should not be used in pregnant or breastfeeding women due to likely harm to the fetus or infant. Trexall has been used in children with juvenile rheumatoid arthritis, but most doses were individualized. Patients taking Trexall should be informed about the many potential severe side effects of this drug, which can be lethal. Some of the more severe problems include GI bleeding, pancreatitis, aplastic anemia, pericarditis, pulmonary embolisms, convulsions, immunodepression, renal failure, abortion, and sudden death. Severe effects occur more frequently in patients taking the high doses of this drug.
Our Trexall Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases, and conditions.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Trexall Prescribing Information: Indications & Dosage
Neoplastic Diseases:
Trexall™ (methotrexate tablets) are indicated in the treatment of gestational choriocarcinoma, chorioadenoma destruens and hydatidiform mole.
Methotrexate is used alone or in combination with other anticancer agents in the treatment of breast cancer, epidermoid cancers of the head and neck, advanced mycosis fungoides, (cutaneous T cell lymphoma), and lung cancer, particularly squamous cell and small cell types. Methotrexate is also used in combination with other chemotherapeutic agents in the treatment of advanced stag...
Read the complete drug monograph for Trexall »
What is Trexall Prescribing Information?
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Trexall Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using methotrexate and call your doctor at once if you have any of these serious side effects:
- dry cough, shortness of breath;
- diarrhea, vomiting, white patches or sores inside your mouth or on your lips;
- blood in your urine or stools;
- urinating less than usual or not at all;
- fever, chills, body aches, flu symptoms;
- sore throat and headache with...
Read the complete patient information for Trexall »
What is Trexall Patient Information?
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
Trexall Consumer Information: Uses
Methotrexate is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis. This medication works by interfering with cell growth and by suppressing the immune system.
Early treatment of rheumatoid arthritis with more aggressive therapy such as methotrexate helps to reduce further joint damage and to preserve joint function.
OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use thi...
Read the complete consumer information for Trexall »
What is Trexall Consumer Information?
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Next: Drug Description
Additional Trexall Information
Trexall - User Reviews
Trexall User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Here is a collection of user reviews for the medication Trexall sorted by most helpful.
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