Treximet (Sumatriptan and Naproxen Sodium Tablets) Patient Information: Side Effects and Drug Images at RxList

Pill Identifier Search

May 27, 2012

Treximet

Migraine »

What is a migraine headache?

A migraine headache is a form of vascular headache. Migraine headache is caused by vasodilatation (enlargement of blood vessels) that causes the release of chemicals from nerve fibers that coil around the large arteries of the brain. Enlargement of these blood vessels stretches the nerves that coil around them and causes the nerves to release chemicals. The chemicals cause inflammation, pain, and further enlargement of the artery. The increasing enlargement of the arteries magnifies the pain.

Migraine attacks commonly activate the sympathetic nervous system in the body. The sympathetic nervous system is often thought of as the part of the nervous system that controls primitive responses to stress and pain, the so-called "fight or flight" response, and this activation causes many of the symptoms associated with migraine attacks; for example, the increased sympathetic nervous activity in the intestine causes nausea, vomiting,...

Read the Migraine article »

« Previous
1
2
3
4
5
6
7
8
9
10
11
12
13
Next »

Treximet User Reviews >>

Treximet

View the Headaches and Migraines Slideshow Pictures

A Visual Guide to Migraine Headaches Slideshow Pictures

Headache and Migraine Triggers Slideshow Pictures

Take the Migraines Quiz

font size

Treximet Patient Information Including Side Effects

Brand Names: Treximet

Generic Name: sumatriptan and naproxen (Pronunciation: soo ma TRIP tan and na PROX en)

What is sumatriptan and naproxen (Treximet)?

Sumatriptan is a headache medicine. It is believed to work by narrowing the blood vessels around the brain. Sumatriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.

Naproxen is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Naproxen works by reducing hormones that cause inflammation and pain in the body.

The combination of sumatriptan and naproxen is used to treat migraine headaches.

Sumatriptan and naproxen will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks. This medication should not be used to treat a migraine that causes visual aura (such as flickering lights) with weakness on one side of the body, speech problems, ringing in your ears.

Sumatriptan and naproxen may also be used for other purposes not listed in this medication guide.

What are the possible side effects of sumatriptan and naproxen (Treximet)?

Get emergency medical help if you have any of these signs of an allergic reaction: runny or stuffy nose; hives; wheezing or trouble breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you a serious side effect such as:

chest pain or pressure, tight feeling in your neck or jaw, pain spreading to your arm or shoulder;
sudden numbness or weakness, confusion, problems with vision, speech, or balance;
bloody, or tarry stools, coughing up blood or vomit that looks like coffee grounds;
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
urinating less than usual or not at all;
pale skin, weakness, easy bruising, flu symptoms;
swelling or rapid weight gain;
numbness, tingling, pale or blue-colored appearance in your fingers or toes;
severe blistering, peeling, and red skin rash;
seizure (convulsions); or
anxiety, restlessness, high fever, sweating, memory problems, trouble concentrating, loss of coordination, vomiting, diarrhea, fast heart rate, hallucinations, or fainting.

Less serious side effects may include:

dizziness, drowsiness;
constipation, dizziness, indigestion, dry mouth;
warmth, numbness, or tingly feeling;
redness in your face;
tight muscles; or
mild pressure or heavy feeling in any part of your body.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about sumatriptan and naproxen

Do not take more than 2 sumatriptan and naproxen tablets in 24 hours.

You should not use this medication if you are allergic to sumatriptan (Imitrex) or naproxen (Aleve, Anaprox, Naprosyn), or if you have a history of asthma or allergic reaction caused by aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs).

Do not take sumatriptan and naproxen if you have liver disease, uncontrolled high blood pressure, or a history of heart disease, angina (chest pain), blood circulation problems, heart attack, stroke, or heart bypass surgery.

Do not take sumatriptan and naproxen if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), selegiline (Eldepryl, Emsam), or phenelzine (Nardil) in the past 14 days.

Do not take sumatriptan and naproxen within 24 hours before or after taking any of the following medications: almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), sumatriptan (Imitrex), or zolmitriptan (Zomig), or ergot medicine such as methysergide (Sansert), ergotamine (Ergomar, Ergostat, Cafergot, Ercaf, Wigraine), dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), ergonovine (Ergotrate), methylergonovine (Methergine).

Related Drug Centers