November 27, 2015
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"The U.S. Food and Drug Administration today approved Aptiom (eslicarbazepine acetate) as an add-on medication to treat seizures associated with epilepsy.

Epilepsy is a brain disorder caused by abnormal or excessive activity in the brain"...


How Supplied


TRIDIONE (trimethadione) is indicated for the control of petit mal seizures that are refractory to treatment with other drugs.


TRIDIONE is administered orally.

Usual Adult Dosage

0.9-2.4 grams daily in 3 or 4 equally divided doses (i.e., 300-600 mg 3 or 4 times daily).

Initially, give 0.9 gram daily; increase this dose by 300 mg at weekly intervals until therapeutic results are seen or until toxic symptoms appear.

Maintenance dosage should be the least amount of drug required to maintain control.

Children's Dosage

Usually 0.3-0.9 gram daily in 3 or 4 equally divided doses.


TRIDIONE Dulcet® Tablets (trimethadione tablets) are supplied as white, chewable tablets bearing the Abbott Logo and a two-letter Abbo-Code designation LE for the 150 mg tablet, in bottles of 100 (NDC 0074-3753-01).

Recommended Storage

Store Dulcet tablets in refrigerator 36° to 46°F (2° - 8°C) to minimize crystallization. However some crystallization not harmful to product may occur. Keep tightly closed.

Abbott Laboratories North Chicago, IL 60064, U.S.A.

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 6/18/2012

How Supplied

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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