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Tridione Patient Information Including Side Effects

Brand Names: Tridione

Generic Name: trimethadione (Pronunciation: try meth ah DYE own)

What is trimethadione (Tridione)?

Trimethadione is a seizure medication. The exact way that it works is unknown.

Trimethadione is used to control absence ("petit mal") seizures.

Trimethadione may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of trimethadione (Tridione)?

If you experience any of the following serious side effects, stop taking trimethadione and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
  • a rash;
  • worsening of seizures;
  • sore throat or fever;
  • changes in vision;
  • easy or unusual bleeding or bruising;
  • bleeding nose; or
  • extreme drowsiness or dizziness.

Other, less serious side effects may be more likely to occur. Continue to take trimethadione and talk to your doctor if you experience

  • mild dizziness, poor coordination, or drowsiness;
  • blurred or double vision, or irregular back-and-forth movements of the eyes;
  • decreased appetite, nausea, or vomiting; or
  • increased sensitivity of the skin to sunlight.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Read the Tridione (trimethadione tablets) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about trimethadione (Tridione)?

Do not stop taking this medication even if you feel better. It is important to continue taking trimethadione to prevent the seizures from recurring.

Carry or wear a medical identification tag to let others know that you are taking this medicine in the case of an emergency.

Use caution when driving, operating machinery, or performing other hazardous activities. Trimethadione may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.

Side Effects Centers

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Find tips and treatments to control seizures.