"THOUSAND OAKS, CA â€” Evolocumab (Repatha, Amgen), a proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor for lowering LDL cholesterol, effectively modifies atherosclerotic plaque buildup in coronary arteries of patients when ad"...
There is no specific treatment for overdose with Triglide. General supportive care of the patient is indicated, including monitoring of vital signs and observation of clinical status, should an overdose occur. If indicated, elimination of unabsorbed drug should be achieved by emesis or gastric lavage; usual precautions should be observed to maintain the airway. Because fenofibrate is highly bound to plasma proteins, hemodialysis should not be considered.
Triglide is contraindicated in:
- Patients with severe renal impairment, including those with end-stage renal disease (ESRD) and those receiving dialysis [see CLINICAL PHARMACOLOGY].
- Patients with active liver disease, including those with primary biliary cirrhosis and unexplained persistent liver function abnormalities [see WARNINGS AND PRECAUTIONS].
- Patients with preexisting gallbladder disease [see WARNINGS AND PRECAUTIONS].
- Patients who have a known hypersensitivity to fenofibrate or fenofibric acid [see WARNINGS AND PRECAUTIONS].
- Nursing mothers [see Use In Specific Populations].
Last reviewed on RxList: 4/30/2015
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