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Before using this product, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: anabolic steroids (e.g., danazol, oxandrolone), anti-platelet drugs (e.g., clopidogrel), "blood thinners" (e.g., enoxaparin, heparin, warfarin), bisphosphonates taken by mouth (e.g., alendronate), carbonic anhydrase inhibitors (e.g., acetazolamide), certain diabetes drugs (sulfonylureas such as glyburide), certain drugs for seizures (phenytoin, phenobarbital, valproic acid), cidofovir, corticosteroids (e.g., prednisone), cyclosporine, drugs for gout (e.g., probenecid, sulfinpyrazone), drugs for high blood pressure (including ACE inhibitors such as captopril, angiotensin II receptor antagonists such as losartan, and beta blockers such as metoprolol), gabapentin, drugs that affect the acidity of urine (e.g., antacids, citrates, sodium bicarbonate, high doses of vitamin C/ascorbic acid), lithium, other drugs that contain magnesium (e.g., milk of magnesia), methotrexate, pemetrexed, tenofovir, "water pills" (diuretics such as furosemide, hydrochlorothiazide, spironolactone).

Check all prescription and nonprescription medicine labels carefully since many contain pain relievers/fever reducers (NSAIDs such as aspirin, ibuprofen, ketorolac, or naproxen) that are similar to this drug and that may increase your risk for side effects if taken together with this medication. Low-dose aspirin should be continued if prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually at dosages of 81-325 milligrams per day). Consult your doctor or pharmacist for more details.

Long-term use of antacids may change how this product works. Ask your doctor or pharmacist about using these products safely.

This medication may interfere with certain laboratory tests (including certain urine glucose tests, thyroid tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: dizziness, ringing in the ears, weakness, drowsiness, fast breathing, confusion, seizures.

NOTES: Do not share this medication with others.

Laboratory and/or medical tests (e.g., blood pressure, complete blood count, liver and kidney function tests, magnesium levels) may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.

If you have arthritis, lifestyle changes (e.g., weight loss if needed, strengthening/conditioning exercises) may help improve your flexibility and joint function. Consult your doctor for specific instructions.

MISSED DOSE: If you are taking this drug on a regular schedule (not "as needed") and you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Store at room temperature between 59-86 degrees F (15-30 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.

Information last revised August 2010 Copyright(c) 2010 First DataBank, Inc.