Trilisate (Choline Magnesium Trisalicylate) Patient Information: Missed a Dose and What Should I Avoid at RxList

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May 27, 2012

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Osteoarthritis is a joint inflammation that results from cartilage degeneration.
Osteoarthritis can be caused by aging, heredity, and injury from trauma or disease.
The most common symptom of osteoarthritis is pain in the affected joint(s) after repetitive use.
There is no blood test for the diagnosis of osteoarthritis.
The goal of treatment in osteoarthritis is to reduce joint pain and inflammation while improving and maintaining joint function.

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Osteoarthritis is a form of arthritis that features the breakdown and eventual loss of the cartilage of one or more joints. Cartilage is a protein substance that serves as a "cushion" between the bones of the joints. Among the over 100 different types of arthritis conditions, osteoarthritis is the most common, affecting over 25 million people in the United Stat...

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Please Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Trilisate Patient Information including If I Miss a Dose

What happens if I miss a dose (Trilisate)?

Since choline magnesium trisalicylate is often used as needed, you may not be on a dosing schedule. If you are using the medication regularly, take the missed dose as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose (Trilisate)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include ringing in your ears, severe dizziness or drowsiness, weakness, confusion, fast breathing, or seizure (convulsions).

What should I avoid while taking choline magnesium trisalicylate (Trilisate)?

If you also take an antibiotic, avoid taking it within 2 hours before or after you take choline magnesium trisalicylate. This medication can make it harder for your body to absorb certain antibiotics.

Do not use any other over-the-counter medication without first asking your doctor or pharmacist. Salicylates and non-steroidal anti-inflammatory drugs (NSAIDs) are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of a certain drug. Read the label of any other medicine you are using to see if it contains aspirin, ibuprofen, naproxen, ketoprofen, magnesium salicylate, or similar medicines.

If you are also taking low-dose aspirin because your doctor has prescribed it to prevent heart attack or stroke, do not stop taking it or change your dose without your doctor's advice. Aspirin should be used for cardiovascular conditions only under the supervision of a doctor.

Avoid alcohol or use it in moderation while taking choline magnesium trisalicylate. If you drink more than three alcoholic beverages a day, the risk of stomach bleeding may increase.

Avoid smoking while you are taking this medication. Smoking can also increase your risk of stomach bleeding.

What other drugs will affect choline magnesium trisalicylate (Trilisate)?

Many drugs can interact with choline magnesium trisalicylate. Below is just a partial list. Tell your doctor if you are using:

acetazolamide (Diamox);
cyclosporine (Gengraf, Neoral, Sandimmune);
gabapentin (Neurontin);
lithium (Eskalith, LithoBid);
methotrexate (Rheumatrex, Trexall);
milk of magnesia;
pemetrexed (Alimta);
tenofovir (Viread);
a blood thinner such as warfarin (Coumadin);
diabetes medication you take by mouth;
a diuretic (water pill);
gout medication such as probenecid (Benemid);
heart or blood pressure medication such as atenolol (Tenormin), captopril (Capoten), lisinopril (Prinivil, Zestril), losartan (Cozaar, Hyzaar), metoprolol (Lopressor, Toprol), and others;
medication used to prevent blood clots, such as clopidogrel (Plavix);
medicine to treat or prevent osteoporosis, such as alendronate (Fosamax), ibandronate (Boniva), risedronate (Actonel), and others;
seizure medication such as phenytoin (Dilantin), phenobarbital (Solfoton), valproic acid (Depakene);
sodium bicarbonate, potassium citrate (K-Lyte, Urocit-K), sodium citrate and citric acid (Bicitra, Oracit), or sodium citrate and potassium (Citrolith, Polycitra); or
steroid medicine (prednisone, danazol (Danocrine), oxandrolone (Oxandrin), and others).

This list is not complete and there are many other medicines that can interact with choline magnesium trisalicylate. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Where can I get more information?

Your pharmacist can provide more information about choline magnesium trisalicylate.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only f or the indication prescribed.

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