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Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Trilisate Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking choline magnesium trisalicylate (Trilisate)?

This medicine may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term. Do not use choline magnesium trisalicylate just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

You should not use this medication if you are allergic to aspirin or to an NSAID, or if you have recently used cidofovir (Vistide), ketorolac (Toradol), or nasal flu vaccine (FluMist).

To make sure you can safely take this medicine, tell your doctor if you have any of these other conditions:

  • heart disease, high blood pressure, congestive heart failure, or a history of stroke or heart attack;
  • a stomach ulcer or intestinal bleeding;
  • a bleeding or blood clotting disorder;
  • diabetes;
  • anemia (a lack of red blood cells);
  • liver or kidney disease;
  • an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);
  • asthma, nasal polyps; or
  • swelling or fluid retention, or if you are dehydrated.

FDA pregnancy category C. Salicylates and NSAIDs may be harmful to an unborn baby if the mother takes the medication during the last 3 months of pregnancy. Tell your doctor if you are pregnant or plan to become pregnant.

Choline magnesium trisalicylate can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Do not give to a child or teenager who has a fever, especially if the child also has flu symptoms or chicken pox. Salicylates can cause a serious and sometimes fatal condition called Reye's syndrome in children.

How should I take choline magnesium trisalicylate (Trilisate)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Take choline magnesium trisalicylate with food, milk, or an antacid if it upsets your stomach. You may need to take the medicine at bedtime, at least 30 minutes before you lie down.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. You may mix the liquid with a small amount of fruit juice to make the medicine taste better. Stir the mixture well and drink all of it right away.

It may take up to 3 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 2 weeks of treatment.

This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you are using choline magnesium trisalicylate.

If you need surgery, tell the surgeon ahead of time that you are using choline magnesium trisalicylate. You may need to stop using the medicine for a short time.

Store at room temperature away from moisture and heat.

Side Effects Centers

Trilisate - User Reviews

Trilisate User Reviews

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Here is a collection of user reviews for the medication Trilisate sorted by most helpful. Patient Discussions FAQs

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