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Trisomy 18
(Edwards Syndrome)

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Trisomy 18 facts

  • Trisomy 18 (Edwards syndrome) results from the presence of an extra copy of chromosome 18.
  • Trisomy 18 leads to severe intellectual and physical defects.
  • The prognosis of trisomy 18 is poor; half of those affected do not live beyond the first week of life and only 10% of infants with this condition live beyond the first year.
  • Common features of trisomy 18 include a low birth weight; a small jaw and mouth; an abnormally shaped, small head; overlapping fingers and clenched fists; and defects in the heart and other organs.
  • Trisomy 18 occurs on average in 1 out of every 6,000 births.
  • Up to 95% of fetuses with trisomy 18 die in the prenatal period (prior to delivery).
  • Girls are affected more commonly than boys.


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Source: MedicineNet.com
http://www.medicinenet.com/trisomy_18/article.htm

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