May 23, 2017
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Trizivir Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking this medication (Trizivir)?

Do not take this medication if you have ever had an allergic reaction to Trizivir or any medicine that contains abacavir, lamivudine, or zidovudine, including: Combivir, Epivir, Epzicom, Retrovir, or Ziagen. Once you have had an allergic reaction to abacavir, you must never use it again.

Some people develop a life-threatening condition called lactic acidosis while taking Trizivir. You may be more likely to develop lactic acidosis if you are overweight or have liver disease, if you are a woman, or if you have taken HIV or AIDS medications for a long time. Talk with your doctor about your individual risk.

This medication can also cause severe or life-threatening effects on your liver. You should not take this medication if you have liver disease, especially hepatitis B or C.

Do not take Trizivir with any of the following HIV medications: Atripla, Combivir, Complera, Emtriva, Epivir, Epzicom, Retrovir, Truvada, Zerit, or Ziagen.

To make sure you can safely take Trizivir, tell your doctor if you have any of these other conditions:

  • bone marrow suppression;
  • kidney disease;
  • heart disease or high blood pressure;
  • a risk factor for heart disease such as smoking, diabetes, or high cholesterol; or
  • if you have used an HIV medication in the past, such as abacavir (Ziagen), didanosine (Videx), emtricitabine (Atripla, Complera, Emtriva, Truvada), lamivudine (Combivir, Epivir, Epzicom), stavudine (Zerit), tenofovir (Viread), zalcitabine (Hivid), or zidovudine (Retrovir).

You may need a blood test before you start taking Trizivir for the first time, or if you are restarting the medication after stopping for reasons not related to an allergic reaction.

FDA pregnancy category C. It is not known whether this medication will harm an unborn baby. HIV can be passed to your baby if you are not properly treated during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Take all of your HIV medicines as directed to control your infection.

Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

Trizivir should not be used to treat HIV in adolescents weighing less than 90 pounds.

How should I take this medication (Trizivir)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

You may take Trizivir with or without food.

Trizivir comes with a Medication Guide and a Warning Card that lists the symptoms of an allergic reaction. Read this information carefully and carry the Warning Card with you at all times so you will know what symptoms to watch for.

Use this medication regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.

While using Trizivir, you may need blood tests at your doctor's office. If you have hepatitis B you may develop liver symptoms after you stop taking this medication, even months after stopping. Your doctor may want to check your liver function for several months after you stop using the medication. Visit your doctor regularly.

Store at room temperature away from moisture and heat.

Side Effects Centers

Trizivir - User Reviews

Trizivir User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Trizivir sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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