Trobicin (Spectinomycin) Drug Information: Side Effects and Drug Interactions

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May 27, 2012

Trobicin

Sexually Transmitted Diseases in Men (STDs in Men) »

What are STDs and how can their spread be prevented?

Sexually transmitted diseases (STDs) are infections that are transmitted during any type of sexual exposure, including intercourse (vaginal or anal), oral sex, and the sharing of sexual devices, such as vibrators. In the professional medical arena, STDs are referred to as STIs (sexually transmitted infections). This terminology is used because many infections are frequently temporary. Some STDs are infections that are transmitted by persistent and close skin-to-skin contact, including during sexual intimacy. Although treatment exists for many STDs, others currently are usually incurable, such as HIV, HPV, hepatitis B and C, and HHV-8. Furthermore, many infections can be present in, and be spread by, patients who do not have symptoms.

The most effective way to prevent the spread of STDs is abstinence. Alternatively, the diligent use of latex barriers, such as condoms, during vaginal or anal...

Read the Sexually Transmitted Diseases in Men (STDs in Men) article »

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Trobicin

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SIDE EFFECTS

The following reactions were observed during the single dose clinical trials: soreness at the injection site, urticaria, dizziness, nausea, chills, fever and insomnia.

During multiple dose subchronic tolerance studies in normal human volunteers, the following were noted: a decrease in hemoglobin, hematocrit and creatinine clearance; elevation of alkaline phosphatase, BUN and SGPT. In single and multiple dose studies in normal volunteers, a reduction in urine output was noted. Extensive renal function studies demonstrated no consistent changes indicative of renal toxicity.

A few cases of anaphylaxis or anaphylactoid reactions have been reported. If serious allergic reactions occur, the usual agents (epinephrine, corticosteroids, and/or antihistamines) should be available for emergency use. In cases of severe anaphylaxis, airway support and oxygen may also be required.