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(amino acid) Injections
Protect from light until use.
TrophAmine (6% and 10% Amino Acid Injections) are sterile, nonpyrogenic, hypertonic solutions containing crystalline amino acids.
All amino acids designated USP are the “L”-isomer with the exception of Glycine USP which does not have an isomer.
Each 100 mL contains:
|Essential Amino Acids||6%||10%|
|Isoleucine USP||0.49 g||0.82 g|
|Leucine USP||0.84 g||1.4 g|
|Lysine||0.49 g||0.82 g|
|(added as Lysine Acetate USP||0.69 g||1.2 g)|
|Methionine USP||0.20 g||0.34 g|
|Phenylalanine USP||0.29 g||0.48 g|
|Threonine USP||0.25 g||0.42 g|
|Tryptophan USP||0.12 g||0.20 g|
|Valine USP||0.47 g||0.78 g|
|Cysteine||< 0.014 g||< 0.016 g|
|(as Cysteine HCI•H2O USP||< 0.020 g||< 0.024 g|
|Histidine USP1||0.29 g||0.48 g|
|Tyrosine1||0.14 g||0.24 g|
|(added as Tyrosine USP||0.044 g||0.044 g|
|and N-Acetyl-L-Tyrosine||0.12 g||0.24 g)|
|Nonessential Amino Acids|
|Alanine USP||0.32 g||0.54 g|
|Arginine USP||0.73 g||1.2 g|
|Proline USP||0.41 g||0.68 g|
|Serine USP||0.23 g||0.38 g|
|Glycine USP||0.22 g||0.36 g|
|L-Aspartic Acid||0.19 g||0.32 g|
|L-Glutamic Acid||0.30 g||0.50 g|
|Taurine2,3||0.015 g||0.025 g|
|Sodium Metabisulfite NF (as an antioxidant)||< 0.050 g||< 0.050 g|
|Water for Injection USP
pH adjusted with Glacial Acetic Acid USP pH: 5.5 (5.0-6.0)
|Calc. Osmolarity (mOsmol/liter)||525||875|
|Total Amino Acids (grams/liter)||60||100|
|Total Nitrogen (grams/liter)||9.3||15.5|
|Protein Equivalent (grams/liter)||58||97|
|Chloride||< 3||< 3|
|*Provided as acetic acid and Iysine acetate.
1 Holt LE, Snyderman SE: The amino acid requirements of infants. JAMA 1961; 175(2):124-127.
2 Rigo J, Senterre J: Is taurine essential for the neonates? Biol Neonate 1977; 32:73-76.
3 Gaull G, Sturman JA, Räihä NCR: Development of mammalian sulfur metabolism: Absence of cystothionase in human fetal tissues. Pediatr Res 1972; 6:538-547.
Last reviewed on RxList: 2/4/2009
This monograph has been modified to include the generic and brand name in many instances.
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