TrophAmine
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TrophAmine
TrophAmine®
(amino acid) Injections
Protect from light until use.
DRUG DESCRIPTION
TrophAmine (6% and 10% Amino Acid Injections) are sterile, nonpyrogenic, hypertonic solutions containing crystalline amino acids.
All amino acids designated USP are the “L”-isomer with the exception of Glycine USP which does not have an isomer.
Each 100 mL contains:
| Essential Amino Acids | 6% | 10% |
| Isoleucine USP | 0.49 g | 0.82 g |
| Leucine USP | 0.84 g | 1.4 g |
| Lysine | 0.49 g | 0.82 g |
| (added as Lysine Acetate USP | 0.69 g | 1.2 g) |
| Methionine USP | 0.20 g | 0.34 g |
| Phenylalanine USP | 0.29 g | 0.48 g |
| Threonine USP | 0.25 g | 0.42 g |
| Tryptophan USP | 0.12 g | 0.20 g |
| Valine USP | 0.47 g | 0.78 g |
| Cysteine | < 0.014 g | < 0.016 g |
| (as Cysteine HCI•H2O USP | < 0.020 g | < 0.024 g |
| Histidine USP1 | 0.29 g | 0.48 g |
| Tyrosine1 | 0.14 g | 0.24 g |
| (added as Tyrosine USP | 0.044 g | 0.044 g |
| and N-Acetyl-L-Tyrosine | 0.12 g | 0.24 g) |
| Nonessential Amino Acids | ||
| Alanine USP | 0.32 g | 0.54 g |
| Arginine USP | 0.73 g | 1.2 g |
| Proline USP | 0.41 g | 0.68 g |
| Serine USP | 0.23 g | 0.38 g |
| Glycine USP | 0.22 g | 0.36 g |
| L-Aspartic Acid | 0.19 g | 0.32 g |
| L-Glutamic Acid | 0.30 g | 0.50 g |
| Taurine2,3 | 0.015 g | 0.025 g |
| Sodium Metabisulfite NF (as an antioxidant) | < 0.050 g | < 0.050 g |
| Water for Injection USP pH adjusted with Glacial Acetic Acid USP pH: 5.5 (5.0-6.0) |
qs | qs |
| Calc. Osmolarity (mOsmol/liter) | 525 | 875 |
| Total Amino Acids (grams/liter) | 60 | 100 |
| Total Nitrogen (grams/liter) | 9.3 | 15.5 |
| Protein Equivalent (grams/liter) | 58 | 97 |
| Electrolytes (mEq/liter) | ||
| Sodium | 5 5 | |
| *Acetate (CH3COO–) | 54.4 | 97 |
| Chloride | < 3 | < 3 |
| *Provided as acetic acid and Iysine acetate.
1 Holt LE, Snyderman SE: The amino acid requirements of infants. JAMA 1961; 175(2):124-127. 2 Rigo J, Senterre J: Is taurine essential for the neonates? Biol Neonate 1977; 32:73-76. 3 Gaull G, Sturman JA, Räihä NCR: Development of mammalian sulfur metabolism: Absence of cystothionase in human fetal tissues. Pediatr Res 1972; 6:538-547. |
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Last reviewed on RxList: 2/4/2009
This monograph has been modified to include the generic and brand name in many instances.
Additional TrophAmine Information
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