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Trusopt Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Trusopt (dorzolamide) is used to treat open-angle glaucoma and other causes of high pressure inside the eye. It is a carbonic anhydrase inhibitor that reduces the amount of fluid in the eye, which decreases pressure inside the eye. This medication is available in generic form. Common side effects include temporary blurred vision, temporary burning/stinging/itching/redness of the eye, watery eyes, dry eyes, sensitivity of eyes to light, bitter taste, or headache.
The dose of Trusopt is one drop in the affected eye(s) three times daily. Trusopt may be used at the same time as other topical ophthalmic drug products to lower intraocular pressure. If more than one topical ophthalmic drug is being used, the drugs should be administered at least ten minutes apart. Trusopt may interact with acetazolamide, dichlorphenamide, or methazolamide. Other drugs may interact with Trusopt ophthalmic. Tell your doctor all prescription and over-the-counter medications you use. Trusopt should be used only when prescribed during pregnancy. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.
Our Trusopt (dorzolamide hydrochloride) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Trusopt in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Although the risk of serious side effects is low when dorzolamide is used in the eyes, you should be aware of side effects that can occur if the medication is absorbed into your bloodstream.
Stop using dorzolamide ophthalmic and call your doctor at once if you have a serious side effect such as:
- swelling or redness of your eyelids;
- eye redness, pain, discomfort, or sensitivity to light;
- drainage, crusting, or oozing of your eyes or eyelids;
- severe skin reaction: fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling; or
- stomach pain, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
- burning or stinging in your eye;
- bitter or unusual taste in your mouth;
- blurred vision;
- dry or watery eyes;
- weakness, tired feeling;
- nausea; or
- dry mouth, sore throat.
Read the entire detailed patient monograph for Trusopt (Dorzolamide Hydrochloride Ophthalmic Solution) »
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Trusopt Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these rare but very serious side effects occur: vision changes, signs of a kidney stone (e.g., pain in the back/side/abdomen, nausea/vomiting, blood in the urine), yellowing eyes or skin, dark urine, unusual tiredness or weakness, easy bruising/bleeding, signs of infection (e.g., fever, chills, persistent sore throat).
Seek immediate medical attention if any of these rare but very serious side effects occur: persistent eye redness or discharge, eye or eyelid swelling, eye pain.
A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Trusopt (Dorzolamide Hydrochloride Ophthalmic Solution)»
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Trusopt FDA Prescribing Information: Side Effects
Clinical Studies Experience
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
Controlled clinical trials
The most frequent adverse reactions associated with TRUSOPT were ocular burning, stinging, or discomfort immediately following ocular administration (approximately one-third of patients). Approximately one-quarter of patients noted a bitter taste following administration. Superficial punctate keratitis occurred in 10 to 15% of patients and signs and symptoms of ocular allergic reaction in approximately 10%. Reactions occurring in approximately 1 to 5% of patients were conjunctivitis and lid reactions [see WARNINGS AND PRECAUTIONS], blurred vision, eye redness, tearing, dryness, and photophobia. Other ocular reactions and systemic reactions were reported infrequently, including headache, nausea, asthenia/fatigue; and, rarely, skin rashes, urolithiasis, and iridocyclitis.
In a 3-month, double-masked, active-treatment-controlled, multicenter study in pediatric patients, the adverse reactions profile of TRUSOPT was comparable to that seen in adult patients.
The following adverse reactions have been identified during post-approval use of TRUSOPT. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure: signs and symptoms of systemic allergic reactions including angioedema, bronchospasm, pruritus, and urticaria; Stevens-Johnson syndrome and toxic epidermal necrolysis; dizziness, paresthesia; ocular pain, transient myopia, choroidal detachment following filtration surgery, eyelid crusting; dyspnea; contact dermatitis, epistaxis, dry mouth and throat irritation.
Read the entire FDA prescribing information for Trusopt (Dorzolamide Hydrochloride Ophthalmic Solution) »
Additional Trusopt Information
Trusopt - User Reviews
Trusopt User Reviews
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