December 2, 2015
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"The US Food and Drug Administration (FDA) today approved asfotase alfa (Strensiq, Alexion Pharmaceuticals) as the first-ever therapy for patients who develop hypophosphatasia, a rare metabolic bone disorder, in childhood.




The health-care provider should instruct patients to report to the health-care provider adverse events such as vesiculation, ulceration or necrosis which may appear at the test site in highly sensitive patients. The health-care provider should also inform the patient that pain, pruritus and discomfort at the site may also occur.

The health-care provider should inform the patient of the need to return for the reading of the test. Self reading of the test has been shown to be unreliable.24 The health-care provider should inform the patient of the need to maintain a personal immunization record.

24. APIC Guidelines Committee. APIC position paper: responsibility for interpretation of the PPD tuberculin skin test. Am J Infect Control 1999;27:56-58.

Last reviewed on RxList: 1/30/2009
This monograph has been modified to include the generic and brand name in many instances.

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